Predicted protein targets (top 14)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | RXRB | P28702 | 6/20 | 0.56 |
| ▸ | RXRA | P19793 | 5/20 | 0.56 |
| ▸ | RXRG | P48443 | 5/20 | 0.56 |
| ▸ | FFAR1 | O14842 | 4/20 | 0.42 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.42 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.41 |
| ▸ | TSHR | P16473 | 1/20 | 0.41 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.41 |
| ▸ | KEAP1 | Q14145 | 1/20 | 0.41 |
| ▸ | FFAR4 | Q5NUL3 | 2/20 | 0.39 |
| ▸ | CYP26A1 | O43174 | 1/20 | 0.39 |
| ▸ | CYP26B1 | Q9NR63 | 1/20 | 0.39 |
| ▸ | NPC1 | O15118 | 1/20 | 0.39 |
| ▸ | RAB9A | P51151 | 1/20 | 0.39 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL2728852 | 0.89 | RXRB (0.67) | RXRBRXRARXRGFFAR1ALDH1A1 | |
| SCHEMBL11111979 | 0.87 | RXRB (0.64) | RXRBRXRARXRGFFAR1ALDH1A1 | |
| SCHEMBL20680969 | 0.82 | RXRA (0.57) | RXRBRXRARXRGFFAR1ALDH1A1 | |
| SCHEMBL30263704 | 0.82 | RXRA (0.57) | RXRBRXRARXRGFFAR1ALDH1A1 | |
| SCHEMBL8766626 | 0.81 | CYP4F2 (0.50) | RXRBRXRARXRGALDH1A1 | |
| SCHEMBL7691902 | 0.80 | RXRB (0.56) | RXRBRXRARXRGALDH1A1ALOX15 | |
| SCHEMBL27697415 | 0.78 | RXRB (0.55) | RXRBRXRARXRGALDH1A1ALOX15 | |
| SCHEMBL7828378 | 0.78 | FFAR4 (0.56) | RXRBRXRARXRGFFAR1ALDH1A1 | |
| SCHEMBL21810616 | 0.77 | RXRB (0.53) | RXRBRXRARXRGFFAR1ALDH1A1 | |
| SCHEMBL8057468 | 0.76 | AKR1B1 (0.54) | RXRBRXRARXRGALDH1A1TSHR |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-1993015041-A1 | ETHANOLAMINE DERIVATIVES HAVING SYMPATHOMIMETIC AND ANTI-POLLAKIURIA ACTIVITIES | FUJISAWA PHARMACEUTICAL CO., LTD. (JP) | 1993-08-05 | — | — | WO | disclosed |