Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HTR2A | P28223 | 5/20 | 0.33 |
| ▸ | HTR2C | P28335 | 5/20 | 0.33 |
| ▸ | ADRA2A | P08913 | 3/20 | 0.33 |
| ▸ | DRD2 | P14416 | 3/20 | 0.33 |
| ▸ | ADRA2C | P18825 | 3/20 | 0.33 |
| ▸ | DRD1 | P21728 | 3/20 | 0.33 |
| ▸ | HRH1 | P35367 | 3/20 | 0.33 |
| ▸ | DRD3 | P35462 | 3/20 | 0.33 |
| ▸ | CHRM2 | P08172 | 1/20 | 0.33 |
| ▸ | HTR1A | P08908 | 1/20 | 0.33 |
| ▸ | GABRA1 | P14867 | 1/20 | 0.33 |
| ▸ | ADRA2B | P18089 | 1/20 | 0.33 |
| ▸ | DRD4 | P21917 | 1/20 | 0.33 |
| ▸ | SLC6A2 | P23975 | 1/20 | 0.33 |
| ▸ | ADRA1D | P25100 | 1/20 | 0.33 |
| ▸ | SLC6A4 | P31645 | 1/20 | 0.33 |
| ▸ | ADRA1A | P35348 | 1/20 | 0.33 |
| ▸ | ADRA1B | P35368 | 1/20 | 0.33 |
| ▸ | HTR2B | P41595 | 1/20 | 0.33 |
| ▸ | HTR3A | P46098 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL11107702 | 0.87 | AR (0.38) | HTR2AHTR2CADRA2ADRD2ADRA2C | |
| SCHEMBL11111959 | 0.85 | ALDH1A1 (0.32) | HTR2AHTR2CADRA2ADRD2ADRA2C | |
| Hydrochloric Acid SCHEMBL11103844 | 0.84 | MEN1 (0.31) | HTR2AARSTK17B | |
| SCHEMBL11107045 | 0.81 | MTNR1A (0.38) | HTR2AHTR2CAR | |
| SCHEMBL11109405 | 0.80 | KDM4E (0.38) | POLB | |
| SCHEMBL11103990 | 0.79 | ALDH1A1 (0.38) | RETKDRARPSMD14STK17B | |
| SCHEMBL11112650 | 0.78 | HTR2A (0.37) | HTR2AHTR2CADRA2ADRD2ADRA2C | |
| SCHEMBL11111226 | 0.75 | POLB (0.35) | HTR2AHTR2CADRA2ADRD2ADRA2C | |
| SCHEMBL11102607 | 0.74 | PGR (0.32) | HTR2AHTR2CADRA2ADRD2ADRA2C | |
| SCHEMBL11106584 | 0.74 | AR (0.39) | DRD2DRD3DRD4ARESR1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-4463001-A | ANTIULCER AGENTS | FARMITALIA CARLO ERBA S.P.A. (IT) | 1984-07-31 | — | — | US | disclosed |