Predicted protein targets (top 14)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.57 |
| ▸ | MAPT | P10636 | 2/20 | 0.57 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.57 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.57 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.57 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.57 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.57 |
| ▸ | POLB | P06746 | 1/20 | 0.56 |
| ▸ | GAA | P10253 | 1/20 | 0.53 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.53 |
| ▸ | KCNH2 | Q12809 | 1/20 | 0.50 |
| ▸ | TSHR | P16473 | 1/20 | 0.48 |
| ▸ | LTA4H | P09960 | 2/20 | 0.47 |
| ▸ | ABCB1 | P08183 | 2/20 | 0.44 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6327217 | 0.85 | POLB (0.61) | ALDH1A1MAPTCYP1A2CYP2D6CYP2C9 | |
| SCHEMBL6327219 | 0.85 | POLB (0.61) | ALDH1A1MAPTCYP1A2CYP2D6CYP2C9 | |
| SCHEMBL11112927 | 0.77 | LTA4H (0.52) | ALDH1A1MAPTMAPK1TSHRLTA4H | |
| SCHEMBL9324850 | 0.77 | SMN1; SMN2 (0.55) | ALDH1A1POLBMAPK1LTA4H | |
| SCHEMBL1140947 | 0.77 | SMN1; SMN2 (0.55) | ALDH1A1POLBMAPK1LTA4H | |
| SCHEMBL20045145 | 0.76 | SMN1; SMN2 (0.51) | ALDH1A1POLBMAPK1TSHRLTA4H | |
| SCHEMBL21759173 | 0.76 | POLB (0.76) | ALDH1A1MAPTCYP1A2CYP2D6CYP2C9 | |
| SCHEMBL9332283 | 0.76 | ALOX5 (0.49) | ALDH1A1POLBMAPK1TSHRLTA4H | |
| SCHEMBL6327241 | 0.75 | POLB (0.61) | ALDH1A1MAPTCYP1A2CYP2D6CYP2C9 | |
| SCHEMBL6327243 | 0.75 | POLB (0.61) | ALDH1A1MAPTCYP1A2CYP2D6CYP2C9 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-4450173-A | BRIEF ACTING B-ADRENERGIC BLOCKING AGENTS; BIOLOGICAL INJECTIONS; ANTIARRYHYTHMIA AGENTS | AMERICAN HOSPITAL SUPPLY CORPORATION (US) | 1984-05-22 | — | — | US | disclosed |
| EP-0053434-A1 | Compounds and method for treatment or prophylaxis of cardiac disorders | AMERICAN HOSPITAL SUPPLY CORPORATION (US) | 1982-06-09 | — | — | EP | disclosed |