SCHEMBL11113053

SCHEMBL11113053

CCCCCCCC(=O)OC(CCOC(=O)CCCC(=O)Oc1cc(Cl)ccc1Oc1ccc(Cl)cc1Cl)OC(=O)CCCCCCC

nearest known ligand 0.49

Predicted protein targets (top 16)

geneUniProtsupporting neighboursconfidence
MAPT P10636 4/20 0.49
ALDH1A1 P00352 2/20 0.47
TDP1 Q9NUW8 2/20 0.47
L3MBTL1 Q9Y468 2/20 0.47
MAPK1 P28482 1/20 0.42
EPHX2 P34913 3/20 0.41
ALOX15 P16050 1/20 0.40
HPGD P15428 5/20 0.39
SMN1; SMN2 Q16637 2/20 0.39
GAA P10253 1/20 0.39
DGKA P23743 1/20 0.38
TSHR P16473 2/20 0.38
MEN1 O00255 2/20 0.38
KMT2A Q03164 2/20 0.38
NPC1 O15118 1/20 0.38
RAB9A P51151 1/20 0.38

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL10884052 1.00 MAPT (0.49) MAPTALDH1A1TDP1L3MBTL1MAPK1
SCHEMBL11114176 0.90 ALDH1A1 (0.45) MAPTALDH1A1TDP1L3MBTL1MAPK1
SCHEMBL14332348 0.87 MAPT (0.53) MAPTALDH1A1TDP1L3MBTL1MAPK1
SCHEMBL10881492 0.86 ALDH1A1 (0.54) MAPTALDH1A1TDP1L3MBTL1MAPK1
SCHEMBL10879742 0.86 ALDH1A1 (0.54) MAPTALDH1A1TDP1L3MBTL1MAPK1
SCHEMBL7067530 0.85 ALOX15 (0.52) MAPTALDH1A1TDP1L3MBTL1MAPK1
SCHEMBL10895571 0.85 ALDH1A1 (0.55) MAPTALDH1A1TDP1L3MBTL1MAPK1
SCHEMBL3439029 0.84 MAPT (0.51) MAPTALDH1A1TDP1L3MBTL1MAPK1
SCHEMBL10882276 0.81 MAPT (0.42) MAPTALDH1A1TDP1L3MBTL1MAPK1
SCHEMBL10883520 0.81 MAPT (0.42) MAPTALDH1A1TDP1L3MBTL1MAPK1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-0099177-A1 Halogenophenyl glyceride esters IMPERIAL CHEMICAL INDUSTRIES PLC (GB) 1984-01-25 EP disclosed