Predicted protein targets (top 12)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | DRD2 | P14416 | 1/20 | 0.35 |
| ▸ | P2RX7 | Q99572 | 1/20 | 0.35 |
| ▸ | SIGMAR1 | Q99720 | 1/20 | 0.34 |
| ▸ | SMPD1 | P17405 | 2/20 | 0.34 |
| ▸ | KCNJ1 | P48048 | 1/20 | 0.33 |
| ▸ | KCNH2 | Q12809 | 1/20 | 0.33 |
| ▸ | PRMT3 | O60678 | 1/20 | 0.33 |
| ▸ | CARM1 | Q86X55 | 1/20 | 0.33 |
| ▸ | PRMT6 | Q96LA8 | 1/20 | 0.33 |
| ▸ | PRMT1 | Q99873 | 1/20 | 0.33 |
| ▸ | PRMT8 | Q9NR22 | 1/20 | 0.33 |
| ▸ | DRD1 | P21728 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL11111188 | 0.89 | ALDH1A1 (0.41) | — | |
| SCHEMBL11151324 | 0.89 | DRD2 (0.38) | DRD2SMPD1DRD1 | |
| SCHEMBL11116042 | 0.87 | P2RX7 (0.36) | P2RX7SIGMAR1DRD1 | |
| SCHEMBL11115905 | 0.85 | DRD2 (0.37) | DRD2P2RX7KCNH2DRD1 | |
| SCHEMBL11112033 | 0.76 | MEN1 (0.39) | — | |
| SCHEMBL10616119 | 0.75 | AKR1B1 (0.48) | — | |
| SCHEMBL9468186 | 0.75 | P2RX7 (0.53) | DRD2P2RX7SIGMAR1SMPD1DRD1 | |
| SCHEMBL11117418 | 0.74 | MAPT (0.46) | DRD2KCNH2 | |
| SCHEMBL11155380 | 0.73 | DRD1 (0.39) | DRD2DRD1 | |
| SCHEMBL10922047 | 0.73 | CHRM5 (0.40) | DRD2SMPD1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0038564-B1 | DIBENZ (B,E) OXEPIN DERIVATIVES AND PHARMACEUTICAL COMPOSITIONS COMPRISING THEM | KYOWA HAKKO KOGYO CO., LTD (JP) | 1984-09-12 | — | — | EP | disclosed |
| US-4396550-A | ANTICHOLINERGIC, ANTIHISTIMINIC AGENTS | KYOWA HAKKO KOGYO CO., LTD. (JP) | 1983-08-02 | — | — | US | disclosed |