Predicted protein targets (top 18)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ACE | P12821 | 3/20 | 0.53 |
| ▸ | MME | P08473 | 1/20 | 0.50 |
| ▸ | LNPEP | Q9UIQ6 | 2/20 | 0.46 |
| ▸ | ERAP2 | Q6P179 | 1/20 | 0.46 |
| ▸ | ERAP1 | Q9NZ08 | 1/20 | 0.46 |
| ▸ | CPB2 | Q96IY4 | 2/20 | 0.44 |
| ▸ | MMP2 | P08253 | 2/20 | 0.43 |
| ▸ | MMP9 | P14780 | 1/20 | 0.43 |
| ▸ | F2 | P00734 | 1/20 | 0.43 |
| ▸ | PLG | P00747 | 1/20 | 0.43 |
| ▸ | PLAT | P00750 | 1/20 | 0.43 |
| ▸ | CPA1 | P15085 | 1/20 | 0.42 |
| ▸ | CPA2 | P48052 | 1/20 | 0.42 |
| ▸ | CPA4 | Q9UI42 | 1/20 | 0.42 |
| ▸ | ITGB3 | P05106 | 1/20 | 0.42 |
| ▸ | ITGA2B | P08514 | 1/20 | 0.42 |
| ▸ | ANPEP | P15144 | 1/20 | 0.42 |
| ▸ | MAOA | P21397 | 1/20 | 0.41 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL1133733 | 1.00 | ACE (0.53) | ACEMMELNPEPERAP2ERAP1 | |
| SCHEMBL4428771 | 0.87 | ACE (0.51) | ACELNPEPERAP2ERAP1ANPEP | |
| SCHEMBL661267 | 0.86 | ACE (0.65) | ACEMMELNPEPERAP2ERAP1 | |
| SCHEMBL5870137 | 0.86 | ACE (0.65) | ACEMMELNPEPERAP2ERAP1 | |
| SCHEMBL7267746 | 0.86 | ACE (0.65) | ACEMMELNPEPERAP2ERAP1 | |
| SCHEMBL7276530 | 0.84 | CTSC (0.53) | ACEMMELNPEPERAP2ERAP1 | |
| SCHEMBL7268746 | 0.84 | CTSC (0.53) | ACEMMELNPEPERAP2ERAP1 | |
| SCHEMBL6064942 | 0.83 | ANPEP (0.42) | ACELNPEPERAP2ERAP1CPB2 | |
| SCHEMBL6064398 | 0.80 | ACE (0.70) | ACEMMELNPEPERAP2ERAP1 | |
| Lysine SCHEMBL6420000 | 0.79 | ACE (0.50) | ACEMMELNPEPERAP2ERAP1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0109020-A2 | Derivatives from tricyclic amino acids, process for their preparation, compounds containing them and their use, as well as bicyclic amino acids as intermediates and process for their preparation | HOECHST AKTIENGESELLSCHAFT (DE) | 1984-05-23 | — | — | EP | disclosed |