SCHEMBL661267

SCHEMBL661267

NCCCC[C@H](N[C@@H](CCc1ccccc1)C(=O)O)C(=O)O

nearest known ligand 0.65

Predicted protein targets (top 19)

geneUniProtsupporting neighboursconfidence
ACE P12821 3/20 0.65
MME P08473 1/20 0.61
MMP2 P08253 1/20 0.52
MMP9 P14780 1/20 0.52
ERAP2 Q6P179 1/20 0.51
ERAP1 Q9NZ08 1/20 0.51
LNPEP Q9UIQ6 1/20 0.51
CPB2 Q96IY4 2/20 0.50
CPA1 P15085 1/20 0.49
CPA2 P48052 1/20 0.49
CPA4 Q9UI42 1/20 0.49
TLR2 O60603 1/20 0.49
MAOA P21397 1/20 0.49
F2 P00734 1/20 0.47
PLG P00747 1/20 0.47
PLAT P00750 1/20 0.47
ITGB3 P05106 1/20 0.46
ITGA2B P08514 1/20 0.46
ANPEP P15144 1/20 0.46

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL7267746 1.00 ACE (0.65) ACEMMEMMP2MMP9ERAP2
SCHEMBL5870137 1.00 ACE (0.65) ACEMMEMMP2MMP9ERAP2
SCHEMBL6237696 0.90 ACE (0.58) ACEMMEMMP2MMP9ERAP2
SCHEMBL27458051 0.90 ACE (0.58) ACEMMEMMP2MMP9ERAP2
SCHEMBL6240311 0.90 ACE (0.58) ACEMMEMMP2MMP9ERAP2
SCHEMBL8255649 0.87 MME (0.68) ACEMME
SCHEMBL29687687 0.87 ACE (0.70) ACEMMEERAP2ERAP1LNPEP
SCHEMBL1133733 0.86 ACE (0.53) ACEMMEMMP2MMP9ERAP2
SCHEMBL6064398 0.86 ACE (0.70) ACEMMEMMP2MMP9ERAP2
SCHEMBL11113260 0.86 ACE (0.53) ACEMMEMMP2MMP9ERAP2

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 21 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-121667277-A CBP lysine children growth milk powder and preparation method thereof 大庆市绿叶乳品有限公司 2026-03-17 CN disclosed
US-11771733-B2 Lisinopril formulations Silvergate Pharmaceuticals, Inc. (US) 2023-10-03 US disclosed
US-20220111000-A1 LISINOPRIL FORMULATIONS HPS INVESTMENT PARTNERS, LLC, AS ADMINISTRATIVE AGENT 2022-04-14 US disclosed
US-11179434-B2 Lisinopril formulations Silvergate Pharmaceuticals Inc. (US) 2021-11-23 US disclosed
US-20210187055-A1 LISINOPRIL FORMULATIONS HPS INVESTMENT PARTNERS, LLC, AS ADMINISTRATIVE AGENT 2021-06-24 US disclosed
US-10940177-B2 Lisinopril formulations Silvergate Pharmaceuticals, Inc. (US) 2021-03-09 US disclosed
US-20200237851-A1 LISINOPRIL FORMULATIONS HPS INVESTMENT PARTNERS, LLC, AS ADMINISTRATIVE AGENT 2020-07-30 US disclosed
US-20200206298-A1 LISINOPRIL FORMULATIONS AZURITY PHARMACEUTICALS, INC. 2020-07-02 US disclosed
US-10406199-B2 Lisinopril formulations Silvergate Pharmaceuticals, Inc. (US) 2019-09-10 US disclosed
US-20190201475-A1 LISINOPRIL FORMULATIONS HPS INVESTMENT PARTNERS, LLC, AS ADMINISTRATIVE AGENT 2019-07-04 US disclosed
US-10039800-B2 Lisinopril formulations Silvergate Pharmaceuticals, Inc. (US) 2018-08-07 US disclosed
US-20180078604-A1 LISINOPRIL FORMULATIONS HPS INVESTMENT PARTNERS, LLC, AS ADMINISTRATIVE AGENT 2018-03-22 US disclosed
US-9814751-B2 Lisinopril formulations Silvergate Pharmaceuticals, Inc. (US) 2017-11-14 US disclosed
US-20170209523-A1 LISINOPRIL FORMULATIONS HPS INVESTMENT PARTNERS, LLC, AS ADMINISTRATIVE AGENT 2017-07-27 US disclosed
US-20170119840-A1 LISINOPRIL FORMULATIONS HPS INVESTMENT PARTNERS, LLC, AS ADMINISTRATIVE AGENT 2017-05-04 US disclosed
US-9616096-B1 Lisinopril formulations Silvergate Pharmaceuticals, Inc. (US) 2017-04-11 US disclosed
US-9463183-B1 Lisinopril formulations Silvergate Pharmaceuticals, Inc. (US) 2016-10-11 US disclosed
US-20120045505-A1 FIXED DOSE DRUG COMBINATION FORMULATIONS DR. REDDY'S LABORATORIES, INC. (US) 2012-02-23 US disclosed
EP-0239062-B1 N2-(1-CARBOXY-3-OXO-3-PHENYLPROPYL)-L-LYSINE COMPOUNDS AND THEIR DERIVATIVES KANEGAFUCHI KAGAKU KOGYO KABUSHIKI KAISHA (JP) 1991-05-29 EP disclosed
EP-0239062-A2 N2-(1-carboxy-3-oxo-3-phenylpropyl)-L-Lysine compounds and their derivatives KANEGAFUCHI KAGAKU KOGYO KABUSHIKI KAISHA (JP) 1987-09-30 EP disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (14 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20210187055-A1 LISINOPRIL FORMULATIONS REN, ACE, AGT ACE 2/4885MME 287/4885MMP2 907/4885
US-20220111000-A1 LISINOPRIL FORMULATIONS REN, ACE, AGT ACE 2/4885MME 287/4885MMP2 907/4885
US-20120045505-A1 FIXED DOSE DRUG COMBINATION FORMULATIONS SLC5A6, TNNT2, SIRT6 ACE 14/4885MME 967/4885MMP2 4690/4885
US-20170209523-A1 LISINOPRIL FORMULATIONS REN, ACE, AGT ACE 2/4885MME 287/4885MMP2 907/4885
US-10406199-B2 Lisinopril formulations REN, ACE, AGT ACE 2/4885MME 287/4885MMP2 907/4885
US-20200206298-A1 LISINOPRIL FORMULATIONS REN, ACE, AGT ACE 2/4885MME 287/4885MMP2 907/4885
US-11179434-B2 Lisinopril formulations REN, ACE, AGT ACE 2/4885MME 287/4885MMP2 907/4885
US-10940177-B2 Lisinopril formulations REN, ACE, AGT ACE 2/4885MME 287/4885MMP2 907/4885
US-10039800-B2 Lisinopril formulations REN, ACE, AGT ACE 2/4885MME 287/4885MMP2 907/4885
US-11771733-B2 Lisinopril formulations REN, ACE, AGT ACE 2/4885MME 287/4885MMP2 907/4885
US-20190201475-A1 LISINOPRIL FORMULATIONS REN, ACE, AGT ACE 2/4885MME 287/4885MMP2 907/4885
US-20170119840-A1 LISINOPRIL FORMULATIONS REN, ACE, AGT ACE 2/4885MME 287/4885MMP2 907/4885
US-20200237851-A1 LISINOPRIL FORMULATIONS REN, ACE, AGT ACE 2/4885MME 287/4885MMP2 907/4885
US-20180078604-A1 LISINOPRIL FORMULATIONS REN, ACE, AGT ACE 2/4885MME 287/4885MMP2 907/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.