Predicted protein targets (top 14)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CTSC | P53634 | 5/20 | 0.53 |
| ▸ | ACE | P12821 | 3/20 | 0.52 |
| ▸ | ANPEP | P15144 | 1/20 | 0.51 |
| ▸ | LNPEP | Q9UIQ6 | 2/20 | 0.48 |
| ▸ | ERAP2 | Q6P179 | 1/20 | 0.48 |
| ▸ | ERAP1 | Q9NZ08 | 1/20 | 0.48 |
| ▸ | MME | P08473 | 1/20 | 0.46 |
| ▸ | MMP2 | P08253 | 1/20 | 0.45 |
| ▸ | MMP9 | P14780 | 1/20 | 0.45 |
| ▸ | CPA1 | P15085 | 1/20 | 0.44 |
| ▸ | CPA2 | P48052 | 1/20 | 0.44 |
| ▸ | CPA4 | Q9UI42 | 1/20 | 0.44 |
| ▸ | CPB2 | Q96IY4 | 1/20 | 0.44 |
| ▸ | TLR2 | O60603 | 1/20 | 0.43 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7268746 | 1.00 | CTSC (0.53) | CTSCACEANPEPLNPEPERAP2 | |
| SCHEMBL5870137 | 0.85 | ACE (0.65) | ACEANPEPLNPEPERAP2ERAP1 | |
| SCHEMBL661267 | 0.85 | ACE (0.65) | ACEANPEPLNPEPERAP2ERAP1 | |
| SCHEMBL7267746 | 0.85 | ACE (0.65) | ACEANPEPLNPEPERAP2ERAP1 | |
| SCHEMBL11113260 | 0.84 | ACE (0.53) | ACEANPEPLNPEPERAP2ERAP1 | |
| SCHEMBL1133733 | 0.84 | ACE (0.53) | ACEANPEPLNPEPERAP2ERAP1 | |
| SCHEMBL7266805 | 0.81 | CTSC (0.44) | CTSCACEMMEMMP2MMP9 | |
| SCHEMBL23680478 | 0.77 | LNPEP (0.66) | ACELNPEPERAP2ERAP1MMP2 | |
| SCHEMBL6240311 | 0.77 | ACE (0.58) | ACEANPEPLNPEPERAP2ERAP1 | |
| SCHEMBL27458051 | 0.77 | ACE (0.58) | ACEANPEPLNPEPERAP2ERAP1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0336368-B1 | N2-(1-carboxy-3-phenylpropyl)-L-lysine derivative and process of producing lysinopril using the compound | KANEGAFUCHI CHEMICAL IND (JP) | 1995-02-01 | — | — | EP | disclosed |
| EP-0336368-A2 | N2-(1-carboxy-3-phenylpropyl)-L-lysine derivative and process of producing lysinopril using the compound | KANEGAFUCHI KAGAKU KOGYO KABUSHIKI KAISHA (JP) | 1989-10-11 | — | — | EP | disclosed |