SCHEMBL11113339

SCHEMBL11113339

C=Cc1ccc(CCc2ccc(C)cc2)cc1

nearest known ligand 0.50

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
ALDH1A1 P00352 2/20 0.50
CYP2A6 P11509 2/20 0.48
CYP1A2 P05177 1/20 0.48
TAAR1 Q96RJ0 1/20 0.48
TP53 P04637 2/20 0.45
MAPT P10636 2/20 0.45
MEN1 O00255 1/20 0.45
KMT2A Q03164 1/20 0.45
KCNH2 Q12809 1/20 0.44
IDO1 P14902 1/20 0.41
CHKA P35790 1/20 0.41
TDP1 Q9NUW8 2/20 0.40
GPR84 Q9NQS5 1/20 0.40
HRH3 Q9Y5N1 1/20 0.39
RAB9A P51151 2/20 0.39
NPC1 O15118 1/20 0.39
SMN1; SMN2 Q16637 1/20 0.39
CA12 O43570 1/20 0.39
CA1 P00915 1/20 0.39
CA2 P00918 1/20 0.39

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL12149353 0.89 MAPT (0.40) ALDH1A1CYP2A6CYP1A2TAAR1TP53
SCHEMBL1647493 0.88 ALDH1A1 (0.65) ALDH1A1TP53MAPTMEN1KMT2A
SCHEMBL50012 0.88 ALDH1A1 (0.65) ALDH1A1TP53MAPTMEN1KMT2A
SCHEMBL18545502 0.86 ALDH1A1 (0.50) ALDH1A1CYP2A6CYP1A2TAAR1TP53
SCHEMBL14658581 0.86 THRB (0.49) ALDH1A1CYP2A6CYP1A2TAAR1TP53
SCHEMBL679555 0.85 ALDH1A1 (0.69) ALDH1A1CYP2A6TP53MAPTMEN1
SCHEMBL14911 0.85
SCHEMBL8975771 0.84 ALDH1A1 (0.48) ALDH1A1CYP2A6TP53MAPTMEN1
Ethane SCHEMBL23051531 0.83 ALDH1A1 (0.65) ALDH1A1CYP2A6TP53MAPTMEN1
Ethylene SCHEMBL10713150 0.83 ALDH1A1 (0.65) ALDH1A1CYP2A6TP53MAPTMEN1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-0103868-A2 Improved electrical insulating oil and oil-filled electrical appliances NIPPON PETROCHEMICALS COMPANY, LIMITED (JP) 1984-03-28 EP disclosed