Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KMT2A | Q03164 | 2/20 | 0.40 |
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.38 |
| ▸ | APEX1 | P27695 | 1/20 | 0.36 |
| ▸ | CA1 | P00915 | 1/20 | 0.36 |
| ▸ | CA2 | P00918 | 1/20 | 0.36 |
| ▸ | CA4 | P22748 | 1/20 | 0.36 |
| ▸ | CA5A | P35218 | 1/20 | 0.36 |
| ▸ | CA5B | Q9Y2D0 | 1/20 | 0.36 |
| ▸ | POLB | P06746 | 2/20 | 0.35 |
| ▸ | GAA | P10253 | 2/20 | 0.33 |
| ▸ | L3MBTL1 | Q9Y468 | 2/20 | 0.33 |
| ▸ | MAPT | P10636 | 2/20 | 0.33 |
| ▸ | HPGD | P15428 | 1/20 | 0.33 |
| ▸ | MEN1 | O00255 | 1/20 | 0.33 |
| ▸ | USP2 | O75604 | 1/20 | 0.33 |
| ▸ | THRB | P10828 | 1/20 | 0.33 |
| ▸ | APOBEC3A | P31941 | 1/20 | 0.33 |
| ▸ | APOBEC3G | Q9HC16 | 1/20 | 0.33 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.33 |
| ▸ | PTGS1 | P23219 | 2/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL13819917 | 0.81 | KMT2A (0.43) | KMT2AALDH1A1APEX1CA1CA2 | |
| SCHEMBL5181029 | 0.80 | — | — | |
| SCHEMBL4822631 | 0.79 | ALDH1A1 (0.59) | KMT2AALDH1A1CA1CA2CA4 | |
| SCHEMBL14582782 | 0.77 | ALDH1A1 (0.47) | KMT2AALDH1A1APEX1CA1CA2 | |
| SCHEMBL8443575 | 0.77 | — | — | |
| SCHEMBL11589488 | 0.74 | APEX1 (0.47) | KMT2AALDH1A1APEX1CA1CA2 | |
| SCHEMBL6261195 | 0.72 | KMT2A (0.50) | KMT2AALDH1A1APEX1CA1CA2 | |
| SCHEMBL2455112 | 0.72 | CA1 (0.41) | KMT2AALDH1A1CA1CA2CA4 | |
| SCHEMBL12313926 | 0.72 | FBP1 (0.48) | KMT2AALDH1A1CA1CA2CA4 | |
| SCHEMBL17550796 | 0.71 | ALDH1A1 (0.64) | KMT2AALDH1A1APEX1GAAL3MBTL1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0127847-A1 | 7-Oxo-4-thia-1-azabicyclo(3.2.0)hept-2-ene derivatives | HOECHST UK LIMITED (GB) | 1984-12-12 | — | — | EP | disclosed |