Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | LMNA | P02545 | 2/20 | 0.37 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.37 |
| ▸ | TP53 | P04637 | 2/20 | 0.37 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.37 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.37 |
| ▸ | MAPT | P10636 | 1/20 | 0.37 |
| ▸ | HPGD | P15428 | 1/20 | 0.37 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.37 |
| ▸ | ALOX12 | P18054 | 1/20 | 0.37 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.37 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.37 |
| ▸ | TAAR1 | Q96RJ0 | 1/20 | 0.37 |
| ▸ | HIF1A | Q16665 | 1/20 | 0.36 |
| ▸ | SMN1; SMN2 | Q16637 | 3/20 | 0.36 |
| ▸ | IDO1 | P14902 | 1/20 | 0.36 |
| ▸ | CA1 | P00915 | 3/20 | 0.35 |
| ▸ | CA2 | P00918 | 3/20 | 0.35 |
| ▸ | CA12 | O43570 | 2/20 | 0.35 |
| ▸ | CA7 | P43166 | 2/20 | 0.35 |
| ▸ | CA9 | Q16790 | 2/20 | 0.35 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL11114275 | 0.84 | LMNA (0.38) | LMNAALDH1A1TP53KDM4ECYP3A4 | |
| SCHEMBL11109543 | 0.81 | SMN1; SMN2 (0.53) | LMNAALDH1A1MAPTTAAR1SMN1; SMN2 | |
| SCHEMBL11113169 | 0.81 | CA12 (0.43) | LMNAALDH1A1KDM4EMAPTMAPK1 | |
| SCHEMBL11114236 | 0.74 | TAAR1 (0.32) | LMNAALDH1A1KDM4EMAPTHPGD | |
| SCHEMBL11109005 | 0.72 | TAAR1 (0.54) | TAAR1IDO1 | |
| SCHEMBL11116134 | 0.71 | CA1 (0.46) | LMNAALDH1A1TP53KDM4ECYP3A4 | |
| SCHEMBL9702070 | 0.71 | TAAR1 (0.40) | LMNAALDH1A1TP53KDM4ECYP3A4 | |
| SCHEMBL11110019 | 0.71 | HSD17B10 (0.56) | HSD17B10TAAR1IDO1CA1CA2 | |
| SCHEMBL11106092 | 0.71 | APLNR (0.49) | ALDH1A1CYP3A4HPGDHSD17B10TAAR1 | |
| SCHEMBL113737 | 0.71 | CA1 (0.50) | LMNAALDH1A1TP53KDM4ECYP3A4 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-4454158-A | Allyl amine MAO inhibitors | MERRELL TORAUDE ET COMPAGNIE (FR) | 1984-06-12 | — | — | US | disclosed |