Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TAAR1 | Q96RJ0 | 1/20 | 0.40 |
| ▸ | LMNA | P02545 | 2/20 | 0.36 |
| ▸ | TP53 | P04637 | 2/20 | 0.36 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.36 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.36 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.36 |
| ▸ | MAPT | P10636 | 1/20 | 0.36 |
| ▸ | HPGD | P15428 | 1/20 | 0.36 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.36 |
| ▸ | ALOX12 | P18054 | 1/20 | 0.36 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.36 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.36 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.35 |
| ▸ | IDO1 | P14902 | 1/20 | 0.35 |
| ▸ | HTR2A | P28223 | 2/20 | 0.35 |
| ▸ | CA1 | P00915 | 3/20 | 0.34 |
| ▸ | CA2 | P00918 | 3/20 | 0.34 |
| ▸ | CA12 | O43570 | 2/20 | 0.34 |
| ▸ | CA7 | P43166 | 2/20 | 0.34 |
| ▸ | CA9 | Q16790 | 2/20 | 0.34 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9702162 | 0.82 | TAAR1 (0.54) | TAAR1LMNAALDH1A1MAPTSMN1; SMN2 | |
| SCHEMBL9702788 | 0.81 | TAAR1 (0.42) | TAAR1KDM4EALDH1A1MAPK1CA1 | |
| SCHEMBL9702039 | 0.78 | SMN1; SMN2 (0.47) | TAAR1LMNAALDH1A1MAPTMAPK1 | |
| SCHEMBL9701676 | 0.74 | KDM4E (0.56) | TAAR1LMNAKDM4EALDH1A1CYP3A4 | |
| SCHEMBL9701633 | 0.73 | TAAR1 (0.57) | TAAR1IDO1 | |
| SCHEMBL9703267 | 0.72 | CA12 (0.44) | TAAR1LMNATP53KDM4EALDH1A1 | |
| SCHEMBL9701904 | 0.72 | ADRA1A (0.58) | TAAR1HSD17B10IDO1HTR2A | |
| SCHEMBL9702802 | 0.72 | ADRA1A (0.50) | TAAR1ALDH1A1CYP3A4HSD17B10CA1 | |
| SCHEMBL11113499 | 0.71 | LMNA (0.37) | TAAR1LMNATP53KDM4EALDH1A1 | |
| SCHEMBL6963550 | 0.70 | TAAR1 (0.61) | TAAR1KDM4ECYP3A4MAPK1HTR2A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5120764-A | Administering penicillamine and allenylamines to inhibit crosslinking of collagen | MERRELL DOW PHARMACEUTICALS INC. (US) | 1992-06-09 | — | — | US | disclosed |
| EP-0374440-A2 | Inhibitors of lysyl oxidase | MERRELL DOW PHARMACEUTICALS INC. (US) | 1990-06-27 | — | — | EP | disclosed |