Predicted protein targets (top 19)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MAPK1 | P28482 | 1/20 | 0.53 |
| ▸ | CYP3A4 | P08684 | 2/20 | 0.53 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.52 |
| ▸ | LMNA | P02545 | 1/20 | 0.49 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.49 |
| ▸ | TSHR | P16473 | 1/20 | 0.48 |
| ▸ | KDM1A | O60341 | 1/20 | 0.48 |
| ▸ | RCOR1 | Q9UKL0 | 1/20 | 0.48 |
| ▸ | CTSL | P07711 | 2/20 | 0.48 |
| ▸ | CTSS | P25774 | 2/20 | 0.48 |
| ▸ | CTSB | P07858 | 1/20 | 0.48 |
| ▸ | CTSK | P43235 | 1/20 | 0.48 |
| ▸ | ATM | Q13315 | 1/20 | 0.48 |
| ▸ | PRSS1 | P07477 | 1/20 | 0.48 |
| ▸ | TPSAB1 | Q15661 | 1/20 | 0.48 |
| ▸ | TPSD1 | Q9BZJ3 | 1/20 | 0.48 |
| ▸ | TPSG1 | Q9NRR2 | 1/20 | 0.48 |
| ▸ | KCNA5 | P22460 | 1/20 | 0.47 |
| ▸ | PLAU | P00749 | 1/20 | 0.47 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL11114231 | 1.00 | MAPK1 (0.53) | MAPK1CYP3A4ALDH1A1LMNASMN1; SMN2 | |
| SCHEMBL11115370 | 1.00 | MAPK1 (0.53) | MAPK1CYP3A4ALDH1A1LMNASMN1; SMN2 | |
| SCHEMBL21563247 | 0.91 | MAPT (0.57) | MAPK1CYP3A4ALDH1A1LMNASMN1; SMN2 | |
| SCHEMBL15375242 | 0.89 | MAPK1 (0.55) | MAPK1CYP3A4ALDH1A1LMNASMN1; SMN2 | |
| SCHEMBL9324497 | 0.89 | MAPK1 (0.55) | MAPK1CYP3A4ALDH1A1LMNASMN1; SMN2 | |
| SCHEMBL12581559 | 0.87 | MAPK1 (0.53) | MAPK1CYP3A4ALDH1A1LMNASMN1; SMN2 | |
| SCHEMBL1687312 | 0.86 | ALDH1A1 (0.60) | MAPK1CYP3A4ALDH1A1LMNASMN1; SMN2 | |
| SCHEMBL2627373 | 0.86 | CTSK (0.59) | LMNACTSLCTSSCTSBCTSK | |
| SCHEMBL591895 | 0.86 | CTSK (0.59) | LMNACTSLCTSSCTSBCTSK | |
| SCHEMBL591894 | 0.86 | CTSK (0.59) | LMNACTSLCTSSCTSBCTSK |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0115473-A2 | Substituted pyrrolidinone derivatives and process for their preparation | CIBA-GEIGY AG (CH) | 1984-08-08 | — | — | EP | disclosed |