SCHEMBL9324497

SCHEMBL9324497

C[C@H](NC(=O)CNC(=O)OCc1ccccc1)C(=O)O

nearest known ligand 0.57

Predicted protein targets (top 14)

geneUniProtsupporting neighboursconfidence
MAPK1 P28482 1/20 0.55
CYP3A4 P08684 2/20 0.55
ALDH1A1 P00352 1/20 0.54
LMNA P02545 1/20 0.51
SMN1; SMN2 Q16637 1/20 0.51
TSHR P16473 1/20 0.50
MME P08473 1/20 0.50
ECE1 P42892 1/20 0.50
CAPN1 P07384 1/20 0.50
ATM Q13315 1/20 0.50
CTSL P07711 1/20 0.50
CTSB P07858 1/20 0.50
CTSS P25774 1/20 0.50
CTSK P43235 1/20 0.50

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL15375242 1.00 MAPK1 (0.55) MAPK1CYP3A4ALDH1A1LMNASMN1; SMN2
SCHEMBL12581559 0.97 MAPK1 (0.53) MAPK1CYP3A4ALDH1A1LMNASMN1; SMN2
SCHEMBL21563247 0.90 MAPT (0.57) MAPK1CYP3A4ALDH1A1LMNASMN1; SMN2
SCHEMBL11113569 0.89 MAPK1 (0.53) MAPK1CYP3A4ALDH1A1LMNASMN1; SMN2
SCHEMBL11114231 0.89 MAPK1 (0.53) MAPK1CYP3A4ALDH1A1LMNASMN1; SMN2
SCHEMBL11115370 0.89 MAPK1 (0.53) MAPK1CYP3A4ALDH1A1LMNASMN1; SMN2
SCHEMBL1687312 0.89 ALDH1A1 (0.60) MAPK1CYP3A4ALDH1A1LMNASMN1; SMN2
SCHEMBL11112981 0.87 CYP3A4 (0.53) MAPK1CYP3A4ALDH1A1LMNATSHR
SCHEMBL30576721 0.87 TPSAB1 (0.60) MAPK1CYP3A4ALDH1A1LMNASMN1; SMN2
SCHEMBL919245 0.86 MAPK1 (0.53) MAPK1CYP3A4ALDH1A1LMNASMN1; SMN2

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 35 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-12590273-B2 Stabilized glycoside hydrolase variants NOVOZYMES A/S (DK) 2026-03-31 US disclosed
US-20260008808-A1 Method for Synthesizing Amide and/or Polypeptide Using Unprotected Amino Acid as Ammonia Component UNIV GUANGZHOU MEDICAL (CN) 2026-01-08 US disclosed
US-12391934-B2 Stabilized cellulase variants NOVOZYMES A/S (DK) 2025-08-19 US disclosed
EP-3953463-B1 STABILIZED GLYCOSIDE HYDROLASE VARIANTS NOVOZYMES AS (DK) 2025-08-06 EP disclosed
EP-4574834-A1 METHOD FOR SYNTHESIZING AMIDE AND/OR POLYPEPTIDE WITH UNPROTECTED AMINO ACID AS AMINE COMPONENT GUANGZHOU MEDICAL UNIVERSITY (CN) 2025-06-25 EP disclosed
US-20250084346-A1 ENCAPSULATED SOLID ENZYME PRODUCT NOVOZYMES A/S (DK) 2025-03-13 US disclosed
US-20250084394-A1 STABILIZED CELLULASE VARIANTS NOVOZYMES A/S (DK) 2025-03-13 US disclosed
CN-119371478-A Method for synthesizing amide and/or polypeptide by taking transient protection amino acid as ammonia component 广州医科大学 2025-01-28 CN disclosed
WO-2025015659-A1 METHOD FOR SYNTHESIZING AMIDE AND/OR POLYPEPTIDE BY TAKING TRANSIENTLY PROTECTED AMINO ACID AS AMMONIA COMPONENT 广州医科大学 2025-01-23 WO disclosed
US-12129498-B2 Stabilized endoglucanase variants NOVOZYMES A/S (DK) 2024-10-29 US disclosed
CN-108603146-B Method for cleaning a medical or dental instrument 诺维信公司 2022-08-02 CN disclosed
US-20220186151-A1 STABILIZED GLYCOSIDE HYDROLASE VARIANTS NOVOZYMES A/S (DK) 2022-06-16 US disclosed
EP-3953463-A1 STABILIZED GLYCOSIDE HYDROLASE VARIANTS Novozymes A/S (DK) 2022-02-16 EP disclosed
EP-0321722-B1 Process for obtaining dipeptides DEGUSSA (DE) 1994-02-16 EP disclosed
EP-0326240-B1 2-Amino acetamide derivatives FISONS CORP (US) 1993-10-20 EP disclosed
EP-0401253-A1 2-AMINO ACETAMIDE DERIVATIVES FISONS CORPORATION (US) 1990-12-12 EP disclosed
US-4871872-A 2-[(2-aminoacetyl)amino]acetamide derivatives FISONS CORPORATION (US) 1989-10-03 US disclosed
EP-0326240-A1 2-Amino acetamide derivatives FISONS CORPORATION (US) 1989-08-02 EP disclosed
WO-1989006646-A1 2-AMINO ACETAMIDE DERIVATIVES FISONS CORPORATION (US) 1989-07-27 WO disclosed
EP-0321722-A2 Process for obtaining dipeptides Degussa Aktiengesellschaft (DE) 1989-06-28 EP disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20260008808-A1 Method for Synthesizing Amide and/or Polypeptide Using Unprotected Amino Acid as Ammonia Component ANPEP, PTMS, GCG MAPK1 2427/4885CYP3A4 2447/4885ALDH1A1 4757/4885
US-12590273-B2 Stabilized glycoside hydrolase variants IDUA, IDE, TREH MAPK1 3202/4885CYP3A4 3052/4885ALDH1A1 2699/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.