Predicted protein targets (top 15)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | SIGMAR1 | Q99720 | 3/20 | 0.45 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.43 |
| ▸ | KDM5A | P29375 | 3/20 | 0.38 |
| ▸ | PHF8 | Q9UPP1 | 3/20 | 0.38 |
| ▸ | KDM2A | Q9Y2K7 | 3/20 | 0.38 |
| ▸ | KDM4C | Q9H3R0 | 2/20 | 0.38 |
| ▸ | KDM4A | O75164 | 1/20 | 0.38 |
| ▸ | METAP1 | P53582 | 1/20 | 0.38 |
| ▸ | EPHX1 | P07099 | 1/20 | 0.37 |
| ▸ | THRB | P10828 | 1/20 | 0.36 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.35 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.35 |
| ▸ | MAPT | P10636 | 1/20 | 0.35 |
| ▸ | NMT2 | O60551 | 1/20 | 0.34 |
| ▸ | NMT1 | P30419 | 1/20 | 0.34 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8585482 | 0.98 | SIGMAR1 (0.48) | SIGMAR1CYP1A2KDM5APHF8KDM2A | |
| SCHEMBL15198681 | 0.92 | SIGMAR1 (0.41) | SIGMAR1CYP1A2KDM5APHF8KDM2A | |
| SCHEMBL15241537 | 0.86 | SIGMAR1 (0.44) | SIGMAR1CYP1A2KDM5APHF8KDM2A | |
| SCHEMBL1111381 | 0.85 | METAP1 (0.46) | SIGMAR1CYP1A2METAP1EPHX1THRB | |
| SCHEMBL11739573 | 0.83 | METAP1 (0.42) | SIGMAR1CYP1A2METAP1THRBALDH1A1 | |
| SCHEMBL10358404 | 0.81 | SIGMAR1 (0.50) | SIGMAR1CYP1A2KDM5APHF8KDM2A | |
| SCHEMBL11462647 | 0.80 | SIGMAR1 (0.50) | SIGMAR1CYP1A2KDM5APHF8KDM2A | |
| SCHEMBL30833259 | 0.79 | SIGMAR1 (0.54) | SIGMAR1CYP1A2KDM5APHF8KDM2A | |
| SCHEMBL9122326 | 0.79 | SIGMAR1 (0.46) | SIGMAR1CYP1A2KDM5APHF8KDM2A | |
| SCHEMBL28126617 | 0.78 | METAP1 (0.41) | SIGMAR1CYP1A2METAP1ALDH1A1KMT2A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 7 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-8829229-B2 | Polyol ethers and process for making them | DOW GLOBAL TECHNOLOGIES LLC (US) | 2014-09-09 | — | — | US | disclosed |
| EP-2318346-B1 | POLYOL ETHERS AND PROCESS FOR MAKING THEM | DOW GLOBAL TECHNOLOGIES LLC (US) | 2013-11-20 | — | — | EP | disclosed |
| EP-2426099-A1 | Coalescent for aqueous compositions | Rohm and Haas Company (US) | 2012-03-07 | — | — | EP | disclosed |
| US-20120052210-A1 | COALESCENT FOR AQUEOUS COMPOSITIONS | VAN DYK ANTONY KEITH (US) | 2012-03-01 | — | — | US | disclosed |
| EP-2318346-A1 | POLYOL ETHERS AND PROCESS FOR MAKING THEM | Dow Global Technologies LLC (US) | 2011-05-11 | — | — | EP | disclosed |
| WO-2010027663-A1 | POLYOL ETHERS AND PROCESS FOR MAKING THEM | DOW GLOBAL TECHNOLOGIES INC. (US) | 2010-03-11 | — | — | WO | disclosed |
| US-20100048940-A1 | reductive etherification of a polyol with an aldehyde or ketone using a hydrogenation catalyt; resulting compounds have use as solvents, surfactants, degreasers, wetting agents, emulsifying agents, lubricants, and intermediates for surfactants; polyols can be from renewable raw materials | DOW GLOBAL TECHNOLOGIES LLC | 2010-02-25 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20100048940-A1 | reductive etherification of a polyol with an aldehyde or ketone using a hydrogenation catalyt; resulting compounds have use as solvents, surfactants, degreasers, wetting agents, emulsifying agents, lubricants, and intermediates for surfactants; polyols can be from renewable raw materials | RNF114, USP14, USP13 | SIGMAR1 605/4885CYP1A2 551/4885KDM5A 1085/4885 |
| US-20120052210-A1 | COALESCENT FOR AQUEOUS COMPOSITIONS | DGAT2, DGAT1, DAGLB | SIGMAR1 804/4885CYP1A2 2037/4885KDM5A 4854/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.