Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | THRB | P10828 | 2/20 | 0.36 |
| ▸ | LMNA | P02545 | 2/20 | 0.35 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.33 |
| ▸ | POLB | P06746 | 1/20 | 0.33 |
| ▸ | HTT | P42858 | 1/20 | 0.33 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.33 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.32 |
| ▸ | TSHR | P16473 | 1/20 | 0.32 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.31 |
| ▸ | MGAM | O43451 | 1/20 | 0.31 |
| ▸ | GAA | P10253 | 1/20 | 0.31 |
| ▸ | SI | P14410 | 1/20 | 0.31 |
| ▸ | MGAM2 | Q2M2H8 | 1/20 | 0.31 |
| ▸ | SOAT1 | P35610 | 1/20 | 0.31 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.31 |
| ▸ | NPC1 | O15118 | 1/20 | 0.31 |
| ▸ | MITF | O75030 | 1/20 | 0.31 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.31 |
| ▸ | RAB9A | P51151 | 1/20 | 0.31 |
| ▸ | FAAH | O00519 | 1/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL11114976 | 0.83 | — | — | |
| SCHEMBL178955 | 0.78 | THRB (0.40) | THRBLMNAALDH1A1HSD17B10ALOX15 | |
| SCHEMBL18658566 | 0.77 | LMNA (0.35) | THRBLMNAFAAH | |
| SCHEMBL11117617 | 0.76 | — | — | |
| SCHEMBL9389312 | 0.75 | ALDH1A1 (0.42) | LMNAALDH1A1POLBHTTSMN1; SMN2 | |
| SCHEMBL23165292 | 0.74 | CYP1A2 (0.36) | THRBLMNAALDH1A1HSD17B10ALOX15 | |
| SCHEMBL6381616 | 0.74 | ALDH1A1 (0.42) | THRBLMNAALDH1A1TSHR | |
| SCHEMBL1126846 | 0.74 | ALDH1A1 (0.44) | THRBLMNAALDH1A1HSD17B10TSHR | |
| SCHEMBL12928910 | 0.73 | — | — | |
| SCHEMBL1702658 | 0.72 | THRB (0.40) | THRBLMNAALDH1A1HSD17B10TSHR |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0122479-A1 | 3-Chloro-1,1-dialkoxy-acetones and process for their preparation | Wacker-Chemie GmbH (DE) | 1984-10-24 | — | — | EP | disclosed |