Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | SETD7 | Q8WTS6 | 1/20 | 0.39 |
| ▸ | DRD2 | P14416 | 4/20 | 0.36 |
| ▸ | DRD4 | P21917 | 4/20 | 0.36 |
| ▸ | HRH4 | Q9H3N8 | 2/20 | 0.36 |
| ▸ | CASP3 | P42574 | 1/20 | 0.35 |
| ▸ | GABRA1 | P14867 | 1/20 | 0.35 |
| ▸ | GABRG2 | P18507 | 1/20 | 0.35 |
| ▸ | GABRB3 | P28472 | 1/20 | 0.35 |
| ▸ | GABRA5 | P31644 | 1/20 | 0.35 |
| ▸ | GABRA3 | P34903 | 1/20 | 0.35 |
| ▸ | GABRA2 | P47869 | 1/20 | 0.35 |
| ▸ | CA12 | O43570 | 1/20 | 0.35 |
| ▸ | CA9 | Q16790 | 1/20 | 0.35 |
| ▸ | ABCB1 | P08183 | 1/20 | 0.34 |
| ▸ | MALT1 | Q9UDY8 | 1/20 | 0.34 |
| ▸ | TP53 | P04637 | 1/20 | 0.34 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.34 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.34 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.34 |
| ▸ | MAPT | P10636 | 1/20 | 0.34 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL10956945 | 0.86 | SETD7 (0.50) | SETD7DRD2DRD4HRH4TP53 | |
| SCHEMBL11116488 | 0.85 | DRD2 (0.36) | DRD2DRD4ABCB1MAPT | |
| SCHEMBL11590816 | 0.78 | SETD7 (0.42) | SETD7DRD2DRD4HRH4TP53 | |
| SCHEMBL11576021 | 0.76 | SETD7 (0.70) | SETD7DRD2DRD4HRH4TP53 | |
| SCHEMBL11399243 | 0.76 | CA12 (0.40) | CASP3CA12CA9 | |
| SCHEMBL11589967 | 0.76 | GAA (0.44) | SETD7ABCB1CYP1A2MAPTCYP2C19 | |
| SCHEMBL11082427 | 0.75 | DRD2 (0.47) | SETD7DRD2HRH4CASP3GABRA1 | |
| SCHEMBL11081947 | 0.73 | TSHR (0.40) | SETD7DRD2DRD4HRH4 | |
| Savoxepin SCHEMBL2110369 | 0.71 | DRD2 (0.40) | DRD2 | |
| SCHEMBL7408056 | 0.71 | HRH4 (0.69) | DRD2DRD4HRH4TP53CYP1A2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0125484-A1 | Polycyclic carboxylic-acid compounds, process for their production, preparations containing such carboxylic-acid compounds and their use | CIBA-GEIGY AG (CH) | 1984-11-21 | — | — | EP | disclosed |