Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | GAA | P10253 | 2/20 | 0.44 |
| ▸ | HTT | P42858 | 2/20 | 0.44 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.44 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.44 |
| ▸ | MAPT | P10636 | 2/20 | 0.44 |
| ▸ | HPGD | P15428 | 2/20 | 0.44 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.44 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.44 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.44 |
| ▸ | NPC1 | O15118 | 1/20 | 0.44 |
| ▸ | ALOX12 | P18054 | 1/20 | 0.44 |
| ▸ | RAB9A | P51151 | 1/20 | 0.44 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.44 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.44 |
| ▸ | HDAC3 | O15379 | 1/20 | 0.40 |
| ▸ | TUBB4A | P04350 | 1/20 | 0.40 |
| ▸ | TUBB | P07437 | 1/20 | 0.40 |
| ▸ | TUBA3C | P0DPH7 | 1/20 | 0.40 |
| ▸ | HDAC4 | P56524 | 1/20 | 0.40 |
| ▸ | TUBA1B | P68363 | 1/20 | 0.40 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL11632788 | 0.85 | GAA (0.41) | GAAHTTKDM4EALDH1A1MAPT | |
| SCHEMBL11590816 | 0.79 | SETD7 (0.42) | ALDH1A1MAPTCYP1A2CYP2C19RAB9A | |
| SCHEMBL11113950 | 0.76 | SETD7 (0.39) | MAPTCYP1A2CYP2C19TDP1SETD7 | |
| SCHEMBL11590923 | 0.74 | NOX1 (0.46) | GAAHTTKDM4EALDH1A1MAPT | |
| SCHEMBL11081947 | 0.74 | TSHR (0.40) | KDM4EALDH1A1SMN1; SMN2SETD7MEN1 | |
| SCHEMBL11110543 | 0.71 | SETD7 (0.44) | ALDH1A1MAPTSMN1; SMN2HDAC3TUBB4A | |
| SCHEMBL13752344 | 0.71 | DRD4 (0.48) | KDM4EALDH1A1MAPTCYP1A2CYP2C9 | |
| Metoxepin SCHEMBL2109740 | 0.71 | DRD2 (0.70) | MAPTCYP1A2CYP2C19TDP1DRD3 | |
| SCHEMBL18417133 | 0.70 | TRPA1 (0.57) | GAAKDM4EALDH1A1MAPTHPGD | |
| SCHEMBL11089511 | 0.70 | SETD7 (0.46) | HTTKDM4EALDH1A1MAPTCYP1A2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-4112110-A | Oxygenated azatetracyclic compounds | CIBA-GEIGY CORPORATION (US) | 1978-09-05 | — | — | US | disclosed |