Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | SSTR3 | P32745 | 4/20 | 0.38 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.36 |
| ▸ | MCOLN2 | Q8IZK6 | 1/20 | 0.36 |
| ▸ | MCOLN1 | Q9GZU1 | 1/20 | 0.36 |
| ▸ | TAS1R3 | Q7RTX0 | 4/20 | 0.35 |
| ▸ | TAS1R1 | Q7RTX1 | 4/20 | 0.35 |
| ▸ | TAS1R2 | Q8TE23 | 4/20 | 0.35 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.35 |
| ▸ | PRKCH | P24723 | 1/20 | 0.34 |
| ▸ | PRKCD | Q05655 | 1/20 | 0.34 |
| ▸ | BTK | Q06187 | 1/20 | 0.34 |
| ▸ | SCN4A | P35499 | 1/20 | 0.34 |
| ▸ | CCR1 | P32246 | 1/20 | 0.33 |
| ▸ | OPRM1 | P35372 | 1/20 | 0.33 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.33 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.33 |
| ▸ | NPC1 | O15118 | 1/20 | 0.33 |
| ▸ | RAB9A | P51151 | 1/20 | 0.33 |
| ▸ | GFER | P55789 | 1/20 | 0.33 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL11119011 | 0.86 | SCN4A (0.36) | MAPK1TAS1R3TAS1R1TAS1R2SCN4A | |
| SCHEMBL11118999 | 0.86 | SCN4A (0.37) | TAS1R3TAS1R1TAS1R2SCN4AOPRM1 | |
| SCHEMBL11121131 | 0.82 | IKZF2 (0.37) | SCN4AOPRM1KDM4E | |
| SCHEMBL11116061 | 0.82 | SCN4A (0.40) | SCN4AOPRM1 | |
| SCHEMBL10500113 | 0.81 | SCN4A (0.39) | SCN4AOPRM1 | |
| SCHEMBL11116317 | 0.81 | SCN4A (0.39) | SCN4AOPRM1 | |
| SCHEMBL11115485 | 0.80 | SCN4A (0.34) | SCN4AOPRM1 | |
| SCHEMBL11115188 | 0.80 | SCN4A (0.39) | SCN4AOPRM1NPSR1 | |
| SCHEMBL11115913 | 0.79 | SLC18A3 (0.45) | SCN4AOPRM1 | |
| SCHEMBL11117599 | 0.78 | LMNA (0.43) | SCN4AOPRM1NPC1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0121972-A2 | N-aryl-alpha-amino-carboxamides | JANSSEN PHARMACEUTICA N.V. (BE) | 1984-10-17 | — | — | EP | disclosed |