Predicted protein targets (top 10)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | SLC18A3 | Q16572 | 2/20 | 0.45 |
| ▸ | OPRM1 | P35372 | 7/20 | 0.36 |
| ▸ | CCR5 | P51681 | 3/20 | 0.36 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.35 |
| ▸ | SCN4A | P35499 | 1/20 | 0.35 |
| ▸ | DDB1 | Q16531 | 1/20 | 0.35 |
| ▸ | CRBN | Q96SW2 | 1/20 | 0.35 |
| ▸ | KCNH2 | Q12809 | 1/20 | 0.35 |
| ▸ | EBP | Q15125 | 1/20 | 0.34 |
| ▸ | IKZF2 | Q9UKS7 | 1/20 | 0.34 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL11116061 | 0.85 | SCN4A (0.40) | OPRM1SCN4A | |
| SCHEMBL10500113 | 0.82 | SCN4A (0.39) | SLC18A3OPRM1SCN4A | |
| SCHEMBL11116317 | 0.82 | SCN4A (0.39) | SLC18A3OPRM1SCN4A | |
| SCHEMBL11121131 | 0.82 | IKZF2 (0.37) | OPRM1SCN4AEBPIKZF2 | |
| SCHEMBL11115188 | 0.81 | SCN4A (0.39) | OPRM1SCN4A | |
| SCHEMBL11117599 | 0.80 | LMNA (0.43) | OPRM1SCN4A | |
| SCHEMBL11118999 | 0.80 | SCN4A (0.37) | OPRM1SCN4AIKZF2 | |
| SCHEMBL11117393 | 0.79 | SCN4A (0.39) | OPRM1SCN4A | |
| SCHEMBL11114296 | 0.79 | SSTR3 (0.38) | OPRM1SCN4A | |
| SCHEMBL11118552 | 0.78 | SCN4A (0.35) | OPRM1SCN4A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0121972-A2 | N-aryl-alpha-amino-carboxamides | JANSSEN PHARMACEUTICA N.V. (BE) | 1984-10-17 | — | — | EP | disclosed |