Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.43 |
| ▸ | HPGD | P15428 | 2/20 | 0.43 |
| ▸ | TSHR | P16473 | 1/20 | 0.43 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.43 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.41 |
| ▸ | MAPT | P10636 | 1/20 | 0.41 |
| ▸ | CACNA1B | Q00975 | 1/20 | 0.41 |
| ▸ | APBA1 | Q02410 | 1/20 | 0.41 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.41 |
| ▸ | APOBEC3G | Q9HC16 | 1/20 | 0.41 |
| ▸ | CYP3A4 | P08684 | 3/20 | 0.39 |
| ▸ | CYP2C9 | P11712 | 2/20 | 0.39 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.39 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.39 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.39 |
| ▸ | CYP4Z1 | Q86W10 | 1/20 | 0.39 |
| ▸ | CYP4F11 | Q9HBI6 | 1/20 | 0.39 |
| ▸ | CYP4F12 | Q9HCS2 | 1/20 | 0.39 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.37 |
| ▸ | ADRA2A | P08913 | 1/20 | 0.37 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL11153211 | 1.00 | ALDH1A1 (0.43) | ALDH1A1HPGDTSHRHSD17B10KDM4E | |
| SCHEMBL11114442 | 1.00 | ALDH1A1 (0.43) | ALDH1A1HPGDTSHRHSD17B10KDM4E | |
| Hydrochloric Acid SCHEMBL11536177 | 0.98 | ALDH1A1 (0.42) | ALDH1A1HPGDTSHRHSD17B10KDM4E | |
| Hydrochloric Acid SCHEMBL11536173 | 0.98 | ALDH1A1 (0.42) | ALDH1A1HPGDTSHRHSD17B10KDM4E | |
| SCHEMBL11142842 | 0.85 | ALDH1A1 (0.44) | ALDH1A1TSHRKDM4EMAPTCYP3A4 | |
| SCHEMBL11420876 | 0.84 | CYP2C9 (0.58) | ALDH1A1HPGDTSHRHSD17B10KDM4E | |
| SCHEMBL11144559 | 0.83 | LMNA (0.43) | ALDH1A1HPGDTSHRHSD17B10KDM4E | |
| SCHEMBL11144562 | 0.83 | LMNA (0.43) | ALDH1A1HPGDTSHRHSD17B10KDM4E | |
| SCHEMBL11454683 | 0.81 | CYP3A4 (0.56) | ALDH1A1HPGDTSHRHSD17B10KDM4E | |
| SCHEMBL6067530 | 0.81 | CYP3A4 (0.56) | ALDH1A1HPGDTSHRHSD17B10KDM4E |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 19 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-9173728-B2 | Multi-cavity container having offset indentures for dispensing fluids | MERIAL INC. (US) | 2015-11-03 | — | — | US | disclosed |
| US-8921408-B2 | Compositions comprising an aryl pyrazole and/or a formamidine, methods and uses thereof | MERIAL LIMITED (US) | 2014-12-30 | — | — | US | disclosed |
| US-20140228785-A1 | COMPOSITIONS COMPRISING AN ARYL PYRAZOLE AND/OR A FORMAMIDINE, METHODS AND USES THEREOF | MERIAL LIMITED (US) | 2014-08-14 | — | — | US | disclosed |
| US-20130256170-A1 | COMPOSITIONS COMPRISING AN ARYL PYRAZOLE AND/OR A FORMAMIDINE, METHODS AND USES THEREOF | MERIAL LIMITED (US) | 2013-10-03 | — | — | US | disclosed |
| US-8450357-B2 | Compositions comprising an aryl pyrazole and/or a formamidine, methods and uses thereof | MERIAL LIMITED (US) | 2013-05-28 | — | — | US | disclosed |
| US-4425361-A | INSECTICIDES, MITICIDES | CIBA-GEIGY CORPORATION (US) | 1984-01-10 | — | — | US | disclosed |
| EP-0022088-B1 | SALTS OF SULPHONIC ACID GROUPS CONTAINING POLYMERS AND THEIR USE AS PESTICIDES | CIBA-GEIGY AG (CH) | 1983-11-23 | — | — | EP | disclosed |
| US-4413013-A | N-(((ARYLFORMAMIDOYL)METHYLAMINO)THIO)-N-SUBSTITUTED SULFONAMIDES | THE UPJOHN COMPANY (US) | 1983-11-01 | — | — | US | disclosed |
| US-4246283-A | Pesticidally active 1-phenyl-1,3,5-triaza-4-sulfa-5-alkylsulfonyl and -phenylsulfonyl-pent-1-en derivatives | CIBA-GEIGY CORPORATION (US) | 1981-01-20 | — | — | US | disclosed |
| US-4223027-A | INSECTICIDES, MITICIDES | CIBA-GEIGY CORPORATION (US) | 1980-09-16 | — | — | US | disclosed |
| US-4136106-A | 1,3,5-TRIAZAPENTA-1,4-DIENE SULFONATE ESTERS | CIBA-GEIGY CORPORATION (US) | 1979-01-23 | — | — | US | disclosed |
| US-4134913-A | MITICIDES | THE UPJOHN COMPANY (US) | 1979-01-16 | — | — | US | disclosed |
| US-4115561-A | N-phenyl-N'methyl-N\"-(O,S-dialkylphosphonyl)-1,3,5-triazapenta-1,4-dienes as pesticides | CIBA-GEIGY CORPORATION (US) | 1978-09-19 | — | — | US | disclosed |
| US-4115583-A | INSECTICIDE, MITICIDE | CIBA-GEIGY CORPORATION (US) | 1978-09-19 | — | — | US | disclosed |
| US-4098902-A | INSECTICIDES AND MITICIDES | CIBA-GEIGY CORPORATION (US) | 1978-07-04 | — | — | US | disclosed |
| US-4066765-A | Arthropodicidal formamidines | THE UPJOHN COMPANY (US) | 1978-01-03 | — | — | US | disclosed |
| US-3998969-A | Formamidine insecticides | THE UPJOHN COMPANY (US) | 1976-12-21 | — | — | US | disclosed |
| US-3954997-A | MITICIDES, INSECTICIDES | THE UPJOHN COMPANY (US) | 1976-05-04 | — | — | US | disclosed |
| US-3947591-A | Pesticidal N,N\"-thio and dithio bis(substituted phenyl formamidines) | THE UPJOHN COMPANY (US) | 1976-03-30 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20130256170-A1 | COMPOSITIONS COMPRISING AN ARYL PYRAZOLE AND/OR A FORMAMIDINE, METHODS AND USES THEREOF | TYR, CAT, NAT1 | ALDH1A1 766/4885HPGD 2433/4885TSHR 4034/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.