Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CYP3A4 | P08684 | 2/20 | 0.56 |
| ▸ | ADRA2A | P08913 | 1/20 | 0.56 |
| ▸ | ALDH1A1 | P00352 | 5/20 | 0.46 |
| ▸ | LMNA | P02545 | 5/20 | 0.46 |
| ▸ | KDM4E | B2RXH2 | 3/20 | 0.46 |
| ▸ | HTT | P42858 | 3/20 | 0.46 |
| ▸ | MAPT | P10636 | 4/20 | 0.45 |
| ▸ | GAA | P10253 | 4/20 | 0.45 |
| ▸ | POLB | P06746 | 1/20 | 0.45 |
| ▸ | THRB | P10828 | 1/20 | 0.45 |
| ▸ | PKM | P14618 | 1/20 | 0.45 |
| ▸ | HPGD | P15428 | 1/20 | 0.45 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.45 |
| ▸ | TSHR | P16473 | 1/20 | 0.45 |
| ▸ | ALOX12 | P18054 | 1/20 | 0.45 |
| ▸ | MPI | P34949 | 1/20 | 0.45 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.45 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.45 |
| ▸ | RAB9A | P51151 | 3/20 | 0.43 |
| ▸ | NPC1 | O15118 | 2/20 | 0.43 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL11454683 | 1.00 | CYP3A4 (0.56) | CYP3A4ADRA2AALDH1A1LMNAKDM4E | |
| Hydrochloric Acid SCHEMBL11533363 | 0.98 | CYP3A4 (0.55) | CYP3A4ADRA2AALDH1A1LMNAKDM4E | |
| SCHEMBL4581102 | 0.86 | CYP3A4 (0.58) | CYP3A4ADRA2AALDH1A1LMNAKDM4E | |
| SCHEMBL11856894 | 0.84 | DHODH (0.45) | CYP3A4ADRA2AALDH1A1LMNAKDM4E | |
| SCHEMBL11779258 | 0.81 | CYP2C9 (0.39) | CYP3A4ADRA2AALDH1A1LMNAKDM4E | |
| SCHEMBL11148348 | 0.81 | NPC1 (0.44) | CYP3A4ADRA2AALDH1A1LMNAKDM4E | |
| SCHEMBL11144303 | 0.81 | SIGMAR1 (0.45) | CYP3A4ADRA2AALDH1A1LMNAKDM4E | |
| SCHEMBL11144308 | 0.81 | SIGMAR1 (0.45) | CYP3A4ADRA2AALDH1A1LMNAKDM4E | |
| SCHEMBL11776909 | 0.81 | CYP2C9 (0.39) | CYP3A4ADRA2AALDH1A1LMNAKDM4E | |
| SCHEMBL11153211 | 0.81 | ALDH1A1 (0.43) | CYP3A4ADRA2AALDH1A1KDM4EMAPT |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 16 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-107778200-B | Process for the preparation of amitraz | 东莞市东阳光动物保健药品有限公司 | 2020-11-24 | — | — | CN | disclosed |
| CN-110724070-A | Crystal form of amitraz and preparation method thereof | 瑞普（天津）生物药业有限公司 | 2020-01-24 | — | — | CN | disclosed |
| US-8921408-B2 | Compositions comprising an aryl pyrazole and/or a formamidine, methods and uses thereof | MERIAL LIMITED (US) | 2014-12-30 | — | — | US | disclosed |
| US-20130256170-A1 | COMPOSITIONS COMPRISING AN ARYL PYRAZOLE AND/OR A FORMAMIDINE, METHODS AND USES THEREOF | MERIAL LIMITED (US) | 2013-10-03 | — | — | US | disclosed |
| WO-2006082213-A1 | COMPOSITIONS FOR CONTROLLING PARASITES COMPRISING SYNERGIC COMBINATION OF AMITRAZ AND CHLORPYRIFOS | INTERVET INTERNATIONAL B.V. (NL) | 2006-08-10 | — | — | WO | disclosed |
| EP-0955331-B1 | Self-water dispersible particle made of biodegradable polyester and process for the preparation thereof | DAINIPPON INK & CHEMICALS (JP) | 2003-09-10 | — | — | EP | disclosed |
| US-4413013-A | N-(((ARYLFORMAMIDOYL)METHYLAMINO)THIO)-N-SUBSTITUTED SULFONAMIDES | THE UPJOHN COMPANY (US) | 1983-11-01 | — | — | US | disclosed |
| US-4186264-A | Triazapentadienes as acaricides | PFIZER INC. (US) | 1980-01-29 | — | — | US | disclosed |
| US-4163056-A | Pesticidal triazapentadienes | CIBA-GEIGY CORPORATION (US) | 1979-07-31 | — | — | US | disclosed |
| US-4154825-A | Arylimidoyl phosphoramidates | ROHM AND HAAS COMPANY (US) | 1979-05-15 | — | — | US | disclosed |
| US-4134913-A | MITICIDES | THE UPJOHN COMPANY (US) | 1979-01-16 | — | — | US | disclosed |
| US-4128652-A | Triazapentadienes as acaricides | PFIZER INC. (US) | 1978-12-05 | — | — | US | disclosed |
| US-4066765-A | Arthropodicidal formamidines | THE UPJOHN COMPANY (US) | 1978-01-03 | — | — | US | disclosed |
| US-3998969-A | Formamidine insecticides | THE UPJOHN COMPANY (US) | 1976-12-21 | — | — | US | disclosed |
| US-3954997-A | MITICIDES, INSECTICIDES | THE UPJOHN COMPANY (US) | 1976-05-04 | — | — | US | disclosed |
| US-3947591-A | Pesticidal N,N\"-thio and dithio bis(substituted phenyl formamidines) | THE UPJOHN COMPANY (US) | 1976-03-30 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20130256170-A1 | COMPOSITIONS COMPRISING AN ARYL PYRAZOLE AND/OR A FORMAMIDINE, METHODS AND USES THEREOF | TYR, CAT, NAT1 | CYP3A4 37/4885ADRA2A 3113/4885ALDH1A1 766/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.