Predicted protein targets (top 16)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | L3MBTL1 | Q9Y468 | 3/20 | 0.39 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.39 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.37 |
| ▸ | PTPRC | P08575 | 1/20 | 0.36 |
| ▸ | LMNA | P02545 | 2/20 | 0.36 |
| ▸ | HPGD | P15428 | 1/20 | 0.36 |
| ▸ | PPARG | P37231 | 3/20 | 0.35 |
| ▸ | PPARA | Q07869 | 3/20 | 0.35 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.35 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.34 |
| ▸ | MAPK8 | P45983 | 1/20 | 0.34 |
| ▸ | MAPK9 | P45984 | 1/20 | 0.34 |
| ▸ | MAPK10 | P53779 | 1/20 | 0.34 |
| ▸ | DHODH | Q02127 | 1/20 | 0.34 |
| ▸ | PPARD | Q03181 | 2/20 | 0.34 |
| ▸ | TACR1 | P25103 | 1/20 | 0.34 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL28587374 | 0.80 | ALDH1A1 (0.46) | L3MBTL1ALDH1A1KMT2APTPRCLMNA | |
| SCHEMBL2820229 | 0.66 | AXL (0.46) | L3MBTL1ALDH1A1KMT2APTPRCLMNA | |
| SCHEMBL12225720 | 0.65 | AXL (0.44) | L3MBTL1ALDH1A1KMT2APTPRCLMNA | |
| SCHEMBL2201666 | 0.64 | ABCC1 (0.44) | L3MBTL1ALDH1A1KMT2APTPRCLMNA | |
| SCHEMBL27581548 | 0.64 | AXL (0.43) | L3MBTL1ALDH1A1KMT2APTPRCLMNA | |
| SCHEMBL25948661 | 0.62 | AXL (0.42) | L3MBTL1ALDH1A1KMT2APTPRCLMNA | |
| SCHEMBL22004403 | 0.62 | ABCC1 (0.42) | L3MBTL1KMT2APTPRCLMNANPSR1 | |
| SCHEMBL16807891 | 0.62 | TYR (0.44) | L3MBTL1ALDH1A1LMNAHPGDPPARG | |
| SCHEMBL30687394 | 0.62 | MAPK8 (0.50) | L3MBTL1ALDH1A1KMT2AHPGDMAPK8 | |
| Hydrochloric Acid SCHEMBL27792423 | 0.62 | SRR (0.47) | L3MBTL1KMT2APPARGPPARAPPARD |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0118867-A2 | Substituted 4,10-dihydro-10-oxothieno benzoxepins, a method of preparing the same and intermediate thereof and their use as medicaments | HOECHST-ROUSSEL PHARMACEUTICALS INCORPORATED (US) | 1984-09-19 | — | — | EP | disclosed |