Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.46 |
| ▸ | L3MBTL1 | Q9Y468 | 2/20 | 0.46 |
| ▸ | PTPRC | P08575 | 1/20 | 0.43 |
| ▸ | ABCC1 | P33527 | 1/20 | 0.42 |
| ▸ | LMNA | P02545 | 4/20 | 0.41 |
| ▸ | POLB | P06746 | 1/20 | 0.41 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.41 |
| ▸ | HTR2A | P28223 | 2/20 | 0.40 |
| ▸ | HRH1 | P35367 | 2/20 | 0.40 |
| ▸ | AXL | P30530 | 1/20 | 0.39 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.39 |
| ▸ | HPGD | P15428 | 1/20 | 0.39 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.38 |
| ▸ | MEN1 | O00255 | 1/20 | 0.38 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.38 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.38 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.38 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.38 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.38 |
| ▸ | TRPM8 | Q7Z2W7 | 1/20 | 0.38 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL11114629 | 0.80 | L3MBTL1 (0.39) | ALDH1A1L3MBTL1PTPRCLMNANPSR1 | |
| SCHEMBL2201666 | 0.79 | ABCC1 (0.44) | ALDH1A1L3MBTL1PTPRCABCC1LMNA | |
| SCHEMBL2820229 | 0.74 | AXL (0.46) | ALDH1A1L3MBTL1PTPRCABCC1LMNA | |
| Bicarbonate SCHEMBL11212986 | 0.73 | LMNA (0.56) | LMNAPOLBHTR2AHRH1TDP1 | |
| Bicarbonate SCHEMBL7184926 | 0.73 | LMNA (0.56) | LMNAPOLBHTR2AHRH1TDP1 | |
| SCHEMBL22004403 | 0.73 | ABCC1 (0.42) | L3MBTL1PTPRCABCC1LMNANPSR1 | |
| SCHEMBL12225720 | 0.73 | AXL (0.44) | ALDH1A1L3MBTL1PTPRCABCC1LMNA | |
| Oxalic Acid SCHEMBL9317952 | 0.72 | LMNA (0.54) | LMNAPOLBHTR2AHRH1TDP1 | |
| SCHEMBL5428376 | 0.72 | ALDH1A1 (0.51) | ALDH1A1LMNAPOLBTDP1HPGD | |
| SCHEMBL27581548 | 0.72 | AXL (0.43) | ALDH1A1L3MBTL1PTPRCABCC1LMNA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-108840864-B | Preparation method and application of tacrine-heterocyclic conjugate | 中国医学科学院生物医学工程研究所 | 2021-07-27 | — | — | CN | disclosed |