Predicted protein targets (top 13)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ACHE | P22303 | 4/20 | 0.51 |
| ▸ | CD274 | Q9NZQ7 | 2/20 | 0.49 |
| ▸ | MEN1 | O00255 | 1/20 | 0.48 |
| ▸ | POLB | P06746 | 1/20 | 0.48 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.48 |
| ▸ | HTR3A | P46098 | 1/20 | 0.47 |
| ▸ | HRH3 | Q9Y5N1 | 4/20 | 0.46 |
| ▸ | KCNH2 | Q12809 | 2/20 | 0.46 |
| ▸ | HRH4 | Q9H3N8 | 2/20 | 0.46 |
| ▸ | HRH1 | P35367 | 1/20 | 0.46 |
| ▸ | FAAH | O00519 | 1/20 | 0.45 |
| ▸ | BCHE | P06276 | 1/20 | 0.45 |
| ▸ | HPGD | P15428 | 1/20 | 0.45 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7229518 | 0.77 | CD274 (0.53) | CD274MEN1KMT2AHPGD | |
| SCHEMBL11116160 | 0.77 | DRD3 (0.77) | KCNH2FAAH | |
| SCHEMBL6027790 | 0.76 | NPC1 (0.50) | KMT2A | |
| SCHEMBL11113965 | 0.76 | DRD3 (0.77) | KCNH2FAAH | |
| SCHEMBL10133070 | 0.75 | HIF1A (0.51) | BCHE | |
| SCHEMBL7230035 | 0.75 | CD274 (0.54) | CD274MEN1KMT2AHPGD | |
| SCHEMBL11118691 | 0.74 | ALDH1A1 (0.48) | — | |
| SCHEMBL11113044 | 0.74 | HRH3 (0.44) | ACHEHRH3BCHE | |
| SCHEMBL8150803 | 0.74 | HPGD (0.76) | CD274MEN1POLBKMT2AHPGD | |
| SCHEMBL11116644 | 0.72 | DRD3 (0.64) | FAAH |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0123700-A1 | Substituted picolinic acids, processes for their preparation, their use, and pharmaceutical preparations containing them | Byk Gulden Lomberg Chemische Fabrik GmbH (DE) | 1984-11-07 | — | — | EP | disclosed |