Predicted protein targets (top 12)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HRH3 | Q9Y5N1 | 7/20 | 0.44 |
| ▸ | HDAC1 | Q13547 | 1/20 | 0.43 |
| ▸ | HDAC6 | Q9UBN7 | 1/20 | 0.43 |
| ▸ | BCHE | P06276 | 2/20 | 0.43 |
| ▸ | ACHE | P22303 | 2/20 | 0.43 |
| ▸ | THRA | P10827 | 2/20 | 0.42 |
| ▸ | THRB | P10828 | 2/20 | 0.42 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.42 |
| ▸ | SPHK1 | Q9NYA1 | 1/20 | 0.42 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.41 |
| ▸ | GLA | P06280 | 1/20 | 0.41 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.41 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL11118776 | 0.90 | HRH3 (0.47) | HRH3BCHEACHECYP2D6 | |
| SCHEMBL11131225 | 0.80 | KCNH2 (0.41) | THRATHRBKDM4ECYP2D6L3MBTL1 | |
| SCHEMBL11118198 | 0.76 | HRH3 (0.46) | HRH3ACHECYP2D6 | |
| SCHEMBL11116202 | 0.76 | ALDH1A1 (0.45) | THRATHRBKDM4ECYP2D6L3MBTL1 | |
| SCHEMBL11114098 | 0.74 | HRH3 (0.50) | HRH3ACHECYP2D6 | |
| SCHEMBL11113046 | 0.74 | HRH3 (0.50) | HRH3ACHECYP2D6 | |
| SCHEMBL11110142 | 0.74 | GAA (0.46) | BCHEKDM4EL3MBTL1 | |
| SCHEMBL11911916 | 0.72 | HRH3 (0.46) | HRH3CYP2D6 | |
| Hydrochloric Acid SCHEMBL4251038 | 0.71 | HRH3 (0.47) | HRH3CYP2D6 | |
| SCHEMBL9367313 | 0.71 | MGLL (0.63) | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0123700-A1 | Substituted picolinic acids, processes for their preparation, their use, and pharmaceutical preparations containing them | Byk Gulden Lomberg Chemische Fabrik GmbH (DE) | 1984-11-07 | — | — | EP | disclosed |