Predicted protein targets (top 10)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TRPA1 | O75762 | 3/20 | 0.46 |
| ▸ | PPARG | P37231 | 3/20 | 0.36 |
| ▸ | RXRA | P19793 | 1/20 | 0.36 |
| ▸ | FLT3 | P36888 | 3/20 | 0.35 |
| ▸ | KCNN4 | O15554 | 1/20 | 0.33 |
| ▸ | MAPT | P10636 | 1/20 | 0.33 |
| ▸ | GPR3 | P46089 | 1/20 | 0.33 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.33 |
| ▸ | MEN1 | O00255 | 1/20 | 0.33 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL11116282 | 1.00 | TRPA1 (0.46) | TRPA1PPARGRXRAFLT3KCNN4 | |
| SCHEMBL29454416 | 0.85 | MEN1 (0.42) | TRPA1MAPTKDM4EMEN1KMT2A | |
| SCHEMBL677773 | 0.85 | MEN1 (0.42) | TRPA1MAPTKDM4EMEN1KMT2A | |
| SCHEMBL8133549 | 0.83 | TRPA1 (0.40) | TRPA1PPARGRXRAMAPTKDM4E | |
| SCHEMBL8133547 | 0.83 | TRPA1 (0.40) | TRPA1PPARGRXRAMAPTKDM4E | |
| SCHEMBL11115877 | 0.82 | S100A4 (0.38) | — | |
| SCHEMBL11115874 | 0.82 | S100A4 (0.38) | — | |
| SCHEMBL11118131 | 0.82 | S100A4 (0.38) | — | |
| SCHEMBL8142361 | 0.80 | TRPA1 (0.40) | TRPA1PPARGRXRA | |
| SCHEMBL8142363 | 0.80 | TRPA1 (0.40) | TRPA1PPARGRXRA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0115690-A1 | Dibenzocycloheptenylidenes | AMERICAN HOME PRODUCTS CORPORATION (US) | 1984-08-15 | — | — | EP | claimed |
| EP-0115690-A1 | Dibenzocycloheptenylidenes | AMERICAN HOME PRODUCTS CORPORATION (US) | 1984-08-15 | — | — | EP | disclosed |