Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | S100A4 | P26447 | 1/20 | 0.38 |
| ▸ | AR | P10275 | 1/20 | 0.35 |
| ▸ | PTGDR2 | Q9Y5Y4 | 1/20 | 0.35 |
| ▸ | PDPK1 | O15530 | 1/20 | 0.35 |
| ▸ | HSD17B3 | P37058 | 1/20 | 0.35 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.35 |
| ▸ | TP53 | P04637 | 1/20 | 0.35 |
| ▸ | IDO1 | P14902 | 1/20 | 0.35 |
| ▸ | TDO2 | P48775 | 1/20 | 0.35 |
| ▸ | TGM2 | P21980 | 1/20 | 0.35 |
| ▸ | CNR2 | P34972 | 1/20 | 0.35 |
| ▸ | LRRK2 | Q5S007 | 1/20 | 0.35 |
| ▸ | CA1 | P00915 | 1/20 | 0.34 |
| ▸ | CA2 | P00918 | 1/20 | 0.34 |
| ▸ | TMPRSS4 | Q9NRS4 | 1/20 | 0.34 |
| ▸ | MITF | O75030 | 1/20 | 0.34 |
| ▸ | HSP90AA1 | P07900 | 1/20 | 0.34 |
| ▸ | HTT | P42858 | 1/20 | 0.34 |
| ▸ | ATM | Q13315 | 1/20 | 0.34 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.34 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL11118131 | 1.00 | S100A4 (0.38) | S100A4ARPTGDR2PDPK1HSD17B3 | |
| SCHEMBL11115874 | 1.00 | S100A4 (0.38) | S100A4ARPTGDR2PDPK1HSD17B3 | |
| SCHEMBL11115316 | 0.91 | HSD17B3 (0.38) | S100A4ARPDPK1HSD17B3ALDH1A1 | |
| SCHEMBL11115938 | 0.91 | HSD17B3 (0.38) | S100A4ARPDPK1HSD17B3ALDH1A1 | |
| SCHEMBL29454416 | 0.85 | MEN1 (0.42) | ALDH1A1TP53IDO1 | |
| SCHEMBL677773 | 0.85 | MEN1 (0.42) | ALDH1A1TP53IDO1 | |
| SCHEMBL11116282 | 0.82 | TRPA1 (0.46) | — | |
| SCHEMBL11114767 | 0.82 | TRPA1 (0.46) | — | |
| SCHEMBL11111667 | 0.78 | HDAC8 (0.40) | ARALDH1A1HTT | |
| SCHEMBL11111670 | 0.78 | HDAC8 (0.40) | ARALDH1A1HTT |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0115690-A1 | Dibenzocycloheptenylidenes | AMERICAN HOME PRODUCTS CORPORATION (US) | 1984-08-15 | — | — | EP | claimed |
| EP-0115690-A1 | Dibenzocycloheptenylidenes | AMERICAN HOME PRODUCTS CORPORATION (US) | 1984-08-15 | — | — | EP | disclosed |