Known targets — ChEMBL curated mechanism
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
The experimentally established mechanism targets of Sulfuric Acid. The predicted profile below is derived independently by chemical similarity — agreement is a validation signal, a miss is honest.
Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | LMNA | P02545 | 5/20 | 0.47 |
| ▸ | EGLN1 | Q9GZT9 | 4/20 | 0.47 |
| ▸ | ALKBH5 | Q6P6C2 | 1/20 | 0.47 |
| ▸ | SUCNR1 | Q9BXA5 | 1/20 | 0.47 |
| ▸ | KDM5C | P41229 | 3/20 | 0.44 |
| ▸ | PHF8 | Q9UPP1 | 3/20 | 0.44 |
| ▸ | KDM2A | Q9Y2K7 | 3/20 | 0.44 |
| ▸ | KDM6B | O15054 | 2/20 | 0.44 |
| ▸ | APEX1 | P27695 | 1/20 | 0.42 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.42 |
| ▸ | SLC15A2 | Q16348 | 1/20 | 0.38 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.38 |
| ▸ | SLC13A3 | Q8WWT9 | 1/20 | 0.38 |
| ▸ | OR51E2 | Q9H255 | 1/20 | 0.38 |
| ▸ | SLC22A6 | Q4U2R8 | 1/20 | 0.36 |
| ▸ | TSHR | P16473 | 4/20 | 0.36 |
| ▸ | NFKB1 | P19838 | 1/20 | 0.35 |
| ▸ | PMP22 | Q01453 | 1/20 | 0.35 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.35 |
| ▸ | FOLH1 | Q04609 | 1/20 | 0.35 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL1992862 | 0.89 | LMNA (0.60) | LMNAEGLN1ALKBH5SUCNR1KDM5C | |
| SCHEMBL288701 | 0.89 | LMNA (0.60) | LMNAEGLN1ALKBH5SUCNR1KDM5C | |
| SCHEMBL27705671 | 0.86 | LMNA (0.56) | LMNAEGLN1ALKBH5SUCNR1KDM5C | |
| SCHEMBL27749051 | 0.86 | LMNA (0.56) | LMNAEGLN1ALKBH5SUCNR1KDM5C | |
| Ammonia Solution, Strong SCHEMBL28163791 | 0.86 | LMNA (0.56) | LMNAEGLN1ALKBH5SUCNR1KDM5C | |
| SCHEMBL2218408 | 0.86 | LMNA (0.56) | LMNAEGLN1ALKBH5SUCNR1KDM5C | |
| Succinic Acid SCHEMBL285597 | 0.83 | LMNA (0.69) | LMNAEGLN1ALKBH5SUCNR1KDM5C | |
| SCHEMBL5633908 | 0.81 | EGLN1 (0.50) | LMNAEGLN1ALKBH5SUCNR1KDM5C | |
| SCHEMBL2209527 | 0.81 | TSHR (0.54) | LMNAEGLN1ALKBH5SUCNR1KDM5C | |
| SCHEMBL429060 | 0.81 | LMNA (0.53) | LMNAEGLN1ALKBH5SUCNR1KDM5C |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0112045-A1 | Detergent compositions | UNILEVER N.V. (NL) | 1984-06-27 | — | — | EP | disclosed |
| EP-0112044-A1 | Detergent compositions | UNILEVER N.V. (NL) | 1984-06-27 | — | — | EP | disclosed |