Predicted protein targets (top 8)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | GAA | P10253 | 1/20 | 0.52 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.52 |
| ▸ | HTT | P42858 | 1/20 | 0.52 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.52 |
| ▸ | EPHX1 | P07099 | 3/20 | 0.51 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.44 |
| ▸ | NAAA | Q02083 | 2/20 | 0.43 |
| ▸ | ACHE | P22303 | 6/20 | 0.41 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL29354750 | 0.97 | GAA (0.57) | GAAMAPK1HTTSMN1; SMN2EPHX1 | |
| SCHEMBL10995376 | 0.94 | GAA (0.60) | GAAMAPK1HTTSMN1; SMN2EPHX1 | |
| SCHEMBL13387564 | 0.92 | GAA (0.59) | GAAMAPK1HTTSMN1; SMN2EPHX1 | |
| SCHEMBL4719490 | 0.92 | GAA (0.59) | GAAMAPK1HTTSMN1; SMN2EPHX1 | |
| SCHEMBL18124429 | 0.90 | EPHX1 (0.46) | GAAMAPK1HTTSMN1; SMN2EPHX1 | |
| SCHEMBL27998887 | 0.89 | GAA (0.51) | GAAMAPK1HTTSMN1; SMN2EPHX1 | |
| SCHEMBL14269207 | 0.88 | GAA (0.43) | GAAMAPK1HTTSMN1; SMN2EPHX1 | |
| SCHEMBL12240761 | 0.88 | TSHR (0.49) | GAAMAPK1HTTSMN1; SMN2EPHX1 | |
| SCHEMBL30849249 | 0.88 | GAA (0.50) | GAAMAPK1HTTSMN1; SMN2EPHX1 | |
| SCHEMBL16526220 | 0.86 | GAA (0.66) | GAAMAPK1HTTSMN1; SMN2EPHX1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 47 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-8927763-B2 | Method for preparing aliphatic diisocyanate | UNIVERSITY-INDUSTRY COOPERATION GROUP OF KYUNG HEE UNIVERSITY (KR) | 2015-01-06 | — | — | US | claimed |
| US-20140303399-A1 | METHOD FOR PREPARING ALIPHATIC DIISOCYANATE | UNIVERSITY-INDUSTRY COOPERATION GROUP OF KYUNG HEE UNIVERSITY (KR) | 2014-10-09 | — | — | US | claimed |
| US-11192853-B2 | Separation method and method for producing isocyanate | ASAHI KASEI CHEMICALS CORPORATION (JP) | 2021-12-07 | — | — | US | disclosed |
| EP-2626345-B1 | SEPARATION METHOD AND METHOD FOR PRODUCING ISOCYANATE | ASAHI CHEMICAL IND (JP) | 2019-01-16 | — | — | EP | disclosed |
| US-20180105489-A1 | Separation Method and Method for Producing Isocyanate | ASAHI KASEI KABUSHIKI KAISHA (JP) | 2018-04-19 | — | — | US | disclosed |
| US-9884810-B2 | Separation method and method for producing isocyanate | ASAHI KASEI CHEMICALS CORPORATION (JP) | 2018-02-06 | — | — | US | disclosed |
| EP-2091911-B1 | PROCESS FOR THE CONTINUOUS PREPARATION OF (CYCLO)ALIPHATIC DIISOCYANATES | EVONIK DEGUSSA GMBH (DE) | 2015-04-29 | — | — | EP | disclosed |
| US-9000219-B2 | Method for treatment of isocyanate residue, and method for treatment of carbonate | MITSUI CHEMICALS, INC. (JP) | 2015-04-07 | — | — | US | disclosed |
| US-8927763-B2 | Method for preparing aliphatic diisocyanate | UNIVERSITY-INDUSTRY COOPERATION GROUP OF KYUNG HEE UNIVERSITY (KR) | 2015-01-06 | — | — | US | disclosed |
| US-20140303399-A1 | METHOD FOR PREPARING ALIPHATIC DIISOCYANATE | UNIVERSITY-INDUSTRY COOPERATION GROUP OF KYUNG HEE UNIVERSITY (KR) | 2014-10-09 | — | — | US | disclosed |
| US-8816125-B2 | Process for the continuous preparation of (cyclo)aliphatic diisocyanates | EVONIK DEGUSSA GMBH (DE) | 2014-08-26 | — | — | US | disclosed |
| US-20050267310-A1 | Phosgene-free; reacting a cycloaliphatic diamine with a carbonic acid derivative and an alcohol to produce a cycloaliphatic diurethane, distillation, thermally cleaving the cycloaliphatic diurethane to produce a cycloaliphatic diisocyanate, recycling reurethanization product directly into the low-boiler | DEGUSSA AG (DE) | 2005-12-01 | — | — | US | disclosed |
| US-20050250960-A1 | Phosgene-free; reacting a cycloaliphatic diamine with a carbonic acid derivative and an alcohol to produce a cycloaliphatic diurethane, distillation, thermally cleaving the cycloaliphatic diurethane to produce a cycloaliphatic diisocyanate, recycling reurethanization product directly into the low-boiler | DEGUSSA AG (DE) | 2005-11-10 | — | — | US | disclosed |
| EP-1593669-A1 | Multi-step process for the continuous preparation of cycloaliphatic diisocyanates | Degussa AG (DE) | 2005-11-09 | — | — | EP | disclosed |
| EP-1512681-A1 | Multi-step process for the continuous preparation of cycloaliphatic diisocyanates | Degussa AG (DE) | 2005-03-09 | — | — | EP | disclosed |
| EP-1512680-A1 | Multi-step process for the continuous preparation of cycloaliphatic diisocyanates | Degussa AG (DE) | 2005-03-09 | — | — | EP | disclosed |
| EP-1512682-A1 | Multi-step process for the continuous preparation of cycloaliphatic diisocyanates | Degussa AG (DE) | 2005-03-09 | — | — | EP | disclosed |
| US-20050043561-A1 | Multistage continuous preparation of cycloaliphatic diisocyanates | DEGUSSA AG (DE) | 2005-02-24 | — | — | US | disclosed |
| US-20050043563-A1 | Multistage continuous preparation of cycloaliphatic diisocyanates | DEGUSSA AG (DE) | 2005-02-24 | — | — | US | disclosed |
| US-20050043562-A1 | Multistage continuous preparation of cycloaliphatic diisocyanates | DEGUSSA AG (DE) | 2005-02-24 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (3 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20140303399-A1 | METHOD FOR PREPARING ALIPHATIC DIISOCYANATE | ALKBH3, DDC, ALKBH5 | GAA 3765/4885MAPK1 4108/4885HTT 612/4885 |
| US-11192853-B2 | Separation method and method for producing isocyanate | IDH3A, IDH3B, CA9 | GAA 2293/4885MAPK1 1889/4885HTT 2386/4885 |
| US-20180105489-A1 | Separation Method and Method for Producing Isocyanate | IDH3A, IDH3B, CA9 | GAA 2293/4885MAPK1 1889/4885HTT 2386/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.