Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ACHE | P22303 | 2/20 | 0.39 |
| ▸ | LMNA | P02545 | 2/20 | 0.38 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.37 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.37 |
| ▸ | SLC6A2 | P23975 | 1/20 | 0.35 |
| ▸ | SLC6A4 | P31645 | 1/20 | 0.35 |
| ▸ | SLC6A3 | Q01959 | 1/20 | 0.35 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.34 |
| ▸ | TSHR | P16473 | 1/20 | 0.34 |
| ▸ | TEAD4 | Q15561 | 1/20 | 0.34 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.34 |
| ▸ | HPGD | P15428 | 1/20 | 0.34 |
| ▸ | TDP1 | Q9NUW8 | 2/20 | 0.33 |
| ▸ | MAPT | P10636 | 2/20 | 0.33 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.33 |
| ▸ | POLB | P06746 | 1/20 | 0.33 |
| ▸ | MEN1 | O00255 | 1/20 | 0.33 |
| ▸ | WDR5 | P61964 | 1/20 | 0.33 |
| ▸ | GRIN2D | O15399 | 1/20 | 0.33 |
| ▸ | GRIN3B | O60391 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL10957293 | 0.87 | SLC6A4 (0.34) | LMNASLC6A2SLC6A4SLC6A3TSHR | |
| SCHEMBL16406624 | 0.78 | ACHE (0.42) | ACHELMNAKMT2ASMN1; SMN2CYP3A4 | |
| SCHEMBL8494832 | 0.78 | HRH3 (0.30) | LMNASLC6A2SLC6A4SLC6A3 | |
| SCHEMBL27653784 | 0.77 | MAPT (0.44) | LMNASMN1; SMN2KDM4EHPGDTDP1 | |
| SCHEMBL24595919 | 0.77 | ACHE (0.41) | ACHELMNAKMT2ASMN1; SMN2CYP3A4 | |
| SCHEMBL1701402 | 0.77 | KDM4E (0.41) | SLC6A4KDM4E | |
| SCHEMBL16406559 | 0.77 | ACHE (0.41) | ACHELMNAKMT2ASMN1; SMN2CYP3A4 | |
| SCHEMBL11502894 | 0.76 | LTA4H (0.47) | TSHR | |
| SCHEMBL27286249 | 0.76 | RXRA (0.34) | — | |
| SCHEMBL18477985 | 0.75 | POLB (0.40) | ACHELMNAKMT2ASMN1; SMN2CYP3A4 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0127143-A2 | Novel aryloxycycloalkanolaminoalkylene aryl ketones | MERRELL DOW PHARMACEUTICALS INC. (US) | 1984-12-05 | — | — | EP | disclosed |