Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KCNH2 | Q12809 | 1/20 | 0.42 |
| ▸ | ESRRG | P62508 | 5/20 | 0.40 |
| ▸ | SIGMAR1 | Q99720 | 4/20 | 0.40 |
| ▸ | ESRRB | O95718 | 2/20 | 0.39 |
| ▸ | ADRA2A | P08913 | 1/20 | 0.38 |
| ▸ | ADRA2B | P18089 | 1/20 | 0.38 |
| ▸ | ADRA2C | P18825 | 1/20 | 0.38 |
| ▸ | ADRA1D | P25100 | 1/20 | 0.38 |
| ▸ | HTR1D | P28221 | 1/20 | 0.38 |
| ▸ | HTR1B | P28222 | 1/20 | 0.38 |
| ▸ | ADRA1A | P35348 | 1/20 | 0.38 |
| ▸ | ADRA1B | P35368 | 1/20 | 0.38 |
| ▸ | GRIA4 | P48058 | 1/20 | 0.37 |
| ▸ | EPHX2 | P34913 | 1/20 | 0.37 |
| ▸ | NR1H4 | Q96RI1 | 1/20 | 0.37 |
| ▸ | APP | P05067 | 1/20 | 0.37 |
| ▸ | SLC13A5 | Q86YT5 | 2/20 | 0.36 |
| ▸ | NPC1 | O15118 | 1/20 | 0.36 |
| ▸ | RAB9A | P51151 | 1/20 | 0.36 |
| ▸ | DAO | P14920 | 1/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL19019721 | 0.86 | KCNH2 (0.42) | KCNH2ESRRGSIGMAR1ESRRBADRA2A | |
| SCHEMBL11116563 | 0.76 | KCNH2 (0.40) | KCNH2ESRRGSIGMAR1ESRRBADRA2A | |
| SCHEMBL2869439 | 0.76 | KCNH2 (0.46) | KCNH2ESRRGSIGMAR1ESRRBGRIA4 | |
| SCHEMBL7456580 | 0.73 | KCNH2 (0.59) | KCNH2ESRRGSIGMAR1ESRRBGRIA4 | |
| SCHEMBL1275239 | 0.73 | KCNH2 (0.47) | KCNH2ESRRGSIGMAR1ESRRBGRIA4 | |
| SCHEMBL11120539 | 0.73 | KCNH2 (0.47) | KCNH2ESRRGSIGMAR1ESRRBGRIA4 | |
| SCHEMBL17753738 | 0.71 | CYP1A2 (0.39) | KCNH2NPC1RAB9A | |
| SCHEMBL22661050 | 0.71 | KCNH2 (0.46) | KCNH2ESRRGSIGMAR1ESRRBADRA2A | |
| SCHEMBL697688 | 0.70 | CA2 (0.52) | KCNH2ESRRGSIGMAR1ESRRBGRIA4 | |
| SCHEMBL31573982 | 0.69 | KCNH2 (0.67) | KCNH2ESRRGSIGMAR1GRIA4NR1H4 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-4469881-A | [2-(p-t-Butylphenyl)ethyl]silanes and method of making the same | PETRARCH SYSTEMS INC. (US) | 1984-09-04 | — | — | US | claimed |