SCHEMBL2869439

SCHEMBL2869439

CC(C)(C)c1ccc(CC[Si](C)(C)Cl)cc1

nearest known ligand 0.46

Predicted protein targets (top 18)

geneUniProtsupporting neighboursconfidence
KCNH2 Q12809 1/20 0.46
ESRRG P62508 5/20 0.42
SIGMAR1 Q99720 4/20 0.42
ESRRB O95718 2/20 0.41
BCHE P06276 1/20 0.41
ACHE P22303 1/20 0.41
CNR1 P21554 1/20 0.41
GRIA4 P48058 1/20 0.40
EPHX2 P34913 1/20 0.40
NR1H4 Q96RI1 1/20 0.40
SLC13A5 Q86YT5 2/20 0.39
MEN1 O00255 1/20 0.39
CYP1A2 P05177 1/20 0.39
CYP2C19 P33261 1/20 0.39
KMT2A Q03164 1/20 0.39
NPC1 O15118 1/20 0.39
RAB9A P51151 1/20 0.39
DAO P14920 1/20 0.39

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL1275239 0.86 KCNH2 (0.47) KCNH2ESRRGSIGMAR1ESRRBCNR1
SCHEMBL11120539 0.86 KCNH2 (0.47) KCNH2ESRRGSIGMAR1ESRRBCNR1
SCHEMBL3195033 0.85 LMNA (0.38) CYP1A2NPC1RAB9A
SCHEMBL11116563 0.80 KCNH2 (0.40) KCNH2ESRRGSIGMAR1ESRRBBCHE
SCHEMBL30064836 0.78 ESRRG (0.45) KCNH2ESRRGSIGMAR1ESRRBCNR1
SCHEMBL7456580 0.78 KCNH2 (0.59) KCNH2ESRRGSIGMAR1ESRRBBCHE
SCHEMBL4848439 0.77 CA2 (0.34)
SCHEMBL6671164 0.77 TAAR1 (0.48) CYP1A2NPC1RAB9A
SCHEMBL28660351 0.76 KCNH2 (0.46) KCNH2ESRRGSIGMAR1ESRRBGRIA4
SCHEMBL4858558 0.76 PPARA (0.42)

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 132 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-4370588-A1 THICK FILM LOW REFRACTIVE INDEX POLYSILOXANE CLADDINGS Optitune Oy (FI) 2024-05-22 EP claimed
WO-2023285739-A1 THICK FILM LOW REFRACTIVE INDEX POLYSILOXANE CLADDINGS OPTITUNE OY (FI) 2023-01-19 WO claimed
US-4469881-A [2-(p-t-Butylphenyl)ethyl]silanes and method of making the same PETRARCH SYSTEMS INC. (US) 1984-09-04 US claimed
US-12109812-B2 Ink jet printing method and ink jet printing apparatus SEIKO EPSON CORPORATION (JP) 2024-10-08 US disclosed
EP-4370588-A1 THICK FILM LOW REFRACTIVE INDEX POLYSILOXANE CLADDINGS Optitune Oy (FI) 2024-05-22 EP disclosed
US-20230256425-A1 INORGANIC POROUS SUBSTRATE, INORGANIC POROUS SUPPORT, AND NUCLEIC ACID PRODUCTION METHOD SUMITOMO CHEMICAL COMPANY, LIMITED (JP) 2023-08-17 US disclosed
US-20230256425-A1 INORGANIC POROUS SUBSTRATE, INORGANIC POROUS SUPPORT, AND NUCLEIC ACID PRODUCTION METHOD SUMITOMO CHEMICAL COMPANY, LIMITED (JP) 2023-08-17 US disclosed
CN-114055975-B Ink jet recording method and ink jet recording apparatus 精工爱普生株式会社 2023-05-12 CN disclosed
WO-2023285739-A1 THICK FILM LOW REFRACTIVE INDEX POLYSILOXANE CLADDINGS OPTITUNE OY (FI) 2023-01-19 WO disclosed
CN-114055975-A Ink jet recording method and ink jet recording apparatus 精工爱普生株式会社 2022-02-18 CN disclosed
US-20220032618-A1 Ink Jet Printing Method And Ink Jet Printing Apparatus SEIKO EPSON CORPORATION (JP) 2022-02-03 US disclosed
US-4976869-A DISSOLVING WATER SOLUBLE SUBSTANCE IN WATER, SELECTIVELY PERMEATING HYDROPHOBIC LAYER OF HOLLOW FIBER MEMBRANE SEPARATION DYNAMICS, INC. (US) 1990-12-11 US disclosed
US-4925963-A Process for reduction of organosilicon halides ETHYL CORPORATION (US) 1990-05-15 US disclosed
US-4923719-A ORGANOFLUOROSILANE ALLIED-SIGNAL INC. (US) 1990-05-08 US disclosed
EP-0357923-A2 Composite semipermeable membranes and method of making same SEPARATION DYNAMICS INC (US) 1990-03-14 EP disclosed
WO-1990002107-A1 A METHOD OF COATING SILICON CARBIDE FIBERS ALLIED-SIGNAL INC. (US) 1990-03-08 WO disclosed
US-4872982-A MULTILAYER HOLLOW FIBER WITH COATING HAVING DIFFERENT PERMEABILITY SEPARATION DYNAMICS, INC. (US) 1989-10-10 US disclosed
EP-0123060-B1 ULTRAPURE CRYSTALLINE SILICA POLYMORPHS AND PROCESS FOR THE PREPARATION THEREOF E.I. DU PONT DE NEMOURS AND COMPANY (US) 1987-11-04 EP disclosed
EP-0123060-A1 Ultrapure crystalline silica polymorphs and process for the preparation thereof E.I. DU PONT DE NEMOURS AND COMPANY (US) 1984-10-31 EP disclosed
US-4469881-A [2-(p-t-Butylphenyl)ethyl]silanes and method of making the same PETRARCH SYSTEMS INC. (US) 1984-09-04 US disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20230256425-A1 INORGANIC POROUS SUBSTRATE, INORGANIC POROUS SUPPORT, AND NUCLEIC ACID PRODUCTION METHOD DNMT3L, FBL, SIK1 KCNH2 2368/4885ESRRG 2628/4885SIGMAR1 923/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.