Predicted protein targets (top 12)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HDAC1 | Q13547 | 14/20 | 0.51 |
| ▸ | HDAC8 | Q9BY41 | 10/20 | 0.50 |
| ▸ | HDAC6 | Q9UBN7 | 11/20 | 0.47 |
| ▸ | HDAC2 | Q92769 | 8/20 | 0.47 |
| ▸ | HDAC3 | O15379 | 7/20 | 0.47 |
| ▸ | HDAC5 | Q9UQL6 | 4/20 | 0.46 |
| ▸ | HDAC4 | P56524 | 3/20 | 0.46 |
| ▸ | HDAC7 | Q8WUI4 | 3/20 | 0.46 |
| ▸ | HDAC10 | Q969S8 | 3/20 | 0.46 |
| ▸ | HDAC11 | Q96DB2 | 3/20 | 0.46 |
| ▸ | HDAC9 | Q9UKV0 | 3/20 | 0.46 |
| ▸ | NCOR2 | Q9Y618 | 1/20 | 0.45 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL3467347 | 0.86 | NR4A2 (0.48) | HDAC1HDAC8HDAC6HDAC2HDAC3 | |
| Hydrochloric Acid SCHEMBL8658431 | 0.84 | NR4A2 (0.47) | HDAC1HDAC8HDAC6HDAC2HDAC3 | |
| SCHEMBL3657378 | 0.77 | ADRA2C (0.46) | HDAC1HDAC8HDAC6HDAC2HDAC3 | |
| SCHEMBL28986867 | 0.75 | ALDH1A1 (0.50) | — | |
| SCHEMBL11119670 | 0.75 | HDAC1 (0.46) | HDAC1HDAC8HDAC6HDAC2HDAC3 | |
| SCHEMBL28194917 | 0.74 | AOC3 (0.50) | — | |
| SCHEMBL13724448 | 0.74 | ADRA2C (0.47) | HDAC1HDAC6HDAC2 | |
| SCHEMBL19248951 | 0.73 | HDAC3 (0.56) | HDAC1HDAC8HDAC6HDAC2HDAC3 | |
| SCHEMBL11218379 | 0.73 | HDAC3 (0.56) | HDAC1HDAC8HDAC6HDAC2HDAC3 | |
| SCHEMBL8657199 | 0.73 | SMN1; SMN2 (0.52) | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0061406-B1 | BENZAMIDO-ALKYL-HYDROXAMIC-ACID DERIVATIVES, PREPARATION THEREOF AND THERAPEUTICAL COMPOSITION | LABORATOIRE L. LAFON Société anonyme dite: (FR) | 1984-06-13 | — | — | EP | claimed |
| US-4407822-A | SEDATIVES | LABORATOIRE L. LAFON (FR) | 1983-10-04 | — | — | US | disclosed |
| US-4407822-A | SEDATIVES | LABORATOIRE L. LAFON (FR) | 1983-10-04 | — | — | US | disclosed |