Predicted protein targets (top 14)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.52 |
| ▸ | ALOX5 | P09917 | 1/20 | 0.46 |
| ▸ | LTA4H | P09960 | 2/20 | 0.45 |
| ▸ | CYP4F2 | P78329 | 2/20 | 0.44 |
| ▸ | CYP4A11 | Q02928 | 2/20 | 0.44 |
| ▸ | TOP2A | P11388 | 2/20 | 0.44 |
| ▸ | TBXAS1 | P24557 | 3/20 | 0.43 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.43 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.42 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.42 |
| ▸ | MEN1 | O00255 | 1/20 | 0.42 |
| ▸ | NPC1 | O15118 | 1/20 | 0.42 |
| ▸ | MAPT | P10636 | 1/20 | 0.42 |
| ▸ | POLB | P06746 | 1/20 | 0.41 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL3467347 | 0.79 | NR4A2 (0.48) | SMN1; SMN2L3MBTL1KMT2AALDH1A1MEN1 | |
| SCHEMBL7769197 | 0.78 | ALOX5 (0.49) | SMN1; SMN2ALOX5LTA4HCYP4F2CYP4A11 | |
| Hydrochloric Acid SCHEMBL7773270 | 0.77 | ALOX5 (0.48) | SMN1; SMN2ALOX5LTA4HCYP4F2CYP4A11 | |
| Hydrochloric Acid SCHEMBL8658431 | 0.77 | NR4A2 (0.47) | SMN1; SMN2L3MBTL1KMT2AALDH1A1MEN1 | |
| SCHEMBL9810832 | 0.76 | SMN1; SMN2 (0.44) | SMN1; SMN2ALOX5CYP4F2CYP4A11L3MBTL1 | |
| SCHEMBL4054017 | 0.76 | HPGD (0.54) | ALDH1A1MAPT | |
| SCHEMBL10850578 | 0.75 | ALOX5 (0.55) | SMN1; SMN2ALOX5LTA4HCYP4F2CYP4A11 | |
| Succinic Acid Diethyl Ester SCHEMBL28851670 | 0.75 | SMN1; SMN2 (0.58) | SMN1; SMN2CYP4F2CYP4A11TOP2ATBXAS1 | |
| SCHEMBL7832398 | 0.75 | ALDH1A1 (0.56) | L3MBTL1ALDH1A1MAPT | |
| SCHEMBL1545820 | 0.74 | HPGD (0.49) | ALDH1A1NPC1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0869944-A1 | N-ACYLPIPERIDINYLCARBONYLAMINOCARBOXYLIC ACIDS AND THEIR USE AS GLYCOPROTEIN IIB/IIa ANTAGONISTS AND FIBRINOGEN-BLOOD PLATELETS BINDING INHIBITORS | FUJISAWA PHARMACEUTICAL CO., LTD. (JP) | 1998-10-14 | — | — | EP | disclosed |