Predicted protein targets (top 9)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | SCN4A | P35499 | 2/20 | 0.42 |
| ▸ | GRM2 | Q14416 | 2/20 | 0.42 |
| ▸ | GRM3 | Q14832 | 2/20 | 0.42 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.41 |
| ▸ | SRC | P12931 | 1/20 | 0.41 |
| ▸ | GABBR2 | O75899 | 1/20 | 0.41 |
| ▸ | GABBR1 | Q9UBS5 | 1/20 | 0.41 |
| ▸ | DPP4 | P27487 | 2/20 | 0.41 |
| ▸ | F2 | P00734 | 1/20 | 0.41 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL29263658 | 0.90 | CYP1A2 (0.47) | CYP2D6 | |
| SCHEMBL288399 | 0.88 | CYP1A2 (0.48) | SCN4AGRM2GRM3CYP2D6GABBR2 | |
| SCHEMBL372488 | 0.88 | CYP1A2 (0.48) | SCN4AGRM2GRM3CYP2D6GABBR2 | |
| SCHEMBL12682235 | 0.88 | CYP1A2 (0.48) | SCN4AGRM2GRM3CYP2D6GABBR2 | |
| Hydrochloric Acid SCHEMBL3017606 | 0.86 | CYP1A2 (0.47) | SCN4AGRM2GRM3CYP2D6GABBR2 | |
| SCHEMBL16015375 | 0.84 | ALDH1A1 (0.47) | SCN4AGRM2GRM3 | |
| SCHEMBL10429552 | 0.84 | ALDH1A1 (0.47) | SCN4AGRM2GRM3 | |
| SCHEMBL8494351 | 0.80 | MTNR1A (0.52) | GRM2GRM3CYP2D6SRC | |
| SCHEMBL10356118 | 0.80 | LTA4H (0.49) | GRM2GRM3CYP2D6GABBR2GABBR1 | |
| SCHEMBL671557 | 0.80 | LTA4H (0.49) | GRM2GRM3CYP2D6GABBR2GABBR1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0110748-A1 | Derivatives of phenyl-(3-aminopropyl) ketone, their therapeutical use and process for their preparation | LABORATOIRE L. LAFON Société anonyme dite: (FR) | 1984-06-13 | — | — | EP | disclosed |