Predicted protein targets (top 14)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | EPHX2 | P34913 | 5/20 | 0.54 |
| ▸ | LMNA | P02545 | 2/20 | 0.51 |
| ▸ | MAPT | P10636 | 4/20 | 0.50 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.50 |
| ▸ | EPHX1 | P07099 | 3/20 | 0.49 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.48 |
| ▸ | GAA | P10253 | 1/20 | 0.48 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.48 |
| ▸ | MEN1 | O00255 | 2/20 | 0.48 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.48 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.46 |
| ▸ | CA1 | P00915 | 1/20 | 0.45 |
| ▸ | CA2 | P00918 | 1/20 | 0.45 |
| ▸ | HTT | P42858 | 1/20 | 0.45 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL22350388 | 0.84 | LMNA (0.50) | LMNAMAPTALDH1A1KDM4EGAA | |
| SCHEMBL11954527 | 0.83 | EPHX2 (0.58) | EPHX2MAPTALDH1A1EPHX1GAA | |
| SCHEMBL1472555 | 0.83 | LMNA (0.66) | LMNAMAPTALDH1A1KDM4EGAA | |
| SCHEMBL11121506 | 0.82 | HDAC3 (0.54) | LMNAMAPTALDH1A1KDM4EGAA | |
| SCHEMBL24258886 | 0.81 | LMNA (0.47) | LMNAMAPTALDH1A1KDM4EGAA | |
| SCHEMBL7593370 | 0.80 | MEN1 (0.51) | LMNAMAPTALDH1A1GAAMEN1 | |
| SCHEMBL8409099 | 0.80 | KDM4E (0.49) | LMNAMAPTALDH1A1KDM4EGAA | |
| SCHEMBL499872 | 0.80 | RAB9A (0.54) | EPHX2LMNAMAPTALDH1A1EPHX1 | |
| SCHEMBL1532303 | 0.79 | MAPT (0.50) | EPHX2LMNAMAPTALDH1A1EPHX1 | |
| Hydrochloric Acid SCHEMBL15646288 | 0.79 | MEN1 (0.50) | LMNAMAPTALDH1A1GAAMEN1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0051828-B1 | N-BENZOYL-ALPHA-ANILINO ALKANE CARBOXYLIC ACIDS, SALTS AND ESTERS THEREOF, PROCESS FOR PRODUCING THE SAME AND PHARMACEUTICAL PREPARATIONS CONTAINING THE SAME | A. Nattermann & Cie. GmbH (DE) | 1984-03-14 | — | — | EP | disclosed |
| US-4386031-A | ANTICOAGULANTS; ANTIALLERGENS; ANTINFLAM-MATORY AND ANTILIPEMIC AGENTS; ANTIHISTAMINES; CARDIOVASCULAR DISORDERS | A. NATTERMANN & CIE GMBH (DE) | 1983-05-31 | — | — | US | disclosed |
| EP-0051828-A1 | N-benzoyl-alpha-anilino alkane carboxylic acids, salts and esters thereof, process for producing the same and pharmaceutical preparations containing the same | A. Nattermann & Cie. GmbH (DE) | 1982-05-19 | — | — | EP | disclosed |