Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MEN1 | O00255 | 7/20 | 0.51 |
| ▸ | KMT2A | Q03164 | 7/20 | 0.51 |
| ▸ | MAPT | P10636 | 5/20 | 0.51 |
| ▸ | LMNA | P02545 | 5/20 | 0.51 |
| ▸ | HTT | P42858 | 3/20 | 0.51 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.51 |
| ▸ | HPGD | P15428 | 2/20 | 0.49 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.49 |
| ▸ | GAA | P10253 | 2/20 | 0.48 |
| ▸ | SMN1; SMN2 | Q16637 | 3/20 | 0.48 |
| ▸ | RAB9A | P51151 | 3/20 | 0.47 |
| ▸ | NPC1 | O15118 | 2/20 | 0.47 |
| ▸ | GRK2 | P25098 | 2/20 | 0.47 |
| ▸ | GRK3 | P35626 | 2/20 | 0.47 |
| ▸ | ROCK2 | O75116 | 1/20 | 0.47 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.47 |
| ▸ | GRK5 | P34947 | 1/20 | 0.46 |
| ▸ | POLB | P06746 | 1/20 | 0.46 |
| ▸ | GFER | P55789 | 1/20 | 0.46 |
| ▸ | VEGFA | P15692 | 1/20 | 0.45 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Hydrochloric Acid SCHEMBL15646288 | 0.98 | MEN1 (0.50) | MEN1KMT2AMAPTLMNAHTT | |
| Cadaverine Tartrate SCHEMBL28777306 | 0.91 | HPGD (0.46) | MEN1KMT2AMAPTLMNAHTT | |
| SCHEMBL5287728 | 0.86 | MAPT (0.54) | MEN1KMT2AMAPTLMNAHTT | |
| SCHEMBL9132938 | 0.84 | MAPT (0.46) | MEN1KMT2AMAPTLMNAHTT | |
| SCHEMBL6239200 | 0.81 | KMT2A (0.47) | MEN1KMT2AMAPTLMNAHTT | |
| SCHEMBL11729327 | 0.81 | MEN1 (0.51) | MEN1KMT2AMAPTLMNAHTT | |
| SCHEMBL28465038 | 0.81 | MEN1 (0.46) | MEN1KMT2AMAPTLMNAHTT | |
| SCHEMBL6243149 | 0.81 | MEN1 (0.51) | MEN1KMT2AMAPTLMNAHTT | |
| SCHEMBL6904254 | 0.81 | ALDH1A1 (0.51) | MEN1KMT2AMAPTALDH1A1HPGD | |
| SCHEMBL9779996 | 0.81 | MAPT (0.56) | MEN1KMT2AMAPTLMNAHTT |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 30 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-114544851-B | Analysis method for determining o-chlorophenylglycine methyl tartrate and impurities | 苏州正济医药研究有限公司 | 2023-12-15 | — | — | CN | disclosed |
| CN-114544851-B | Analysis method for determining o-chlorophenylglycine methyl tartrate and impurities | 苏州正济医药研究有限公司 | 2023-12-15 | — | — | CN | disclosed |
| WO-2023055702-A1 | MAIN PROTEASE (M PRO) INHIBITORS AND METHODS USING SAME | ARBUTUS BIOPHARMA CORPORATION (CA) | 2023-04-06 | — | — | WO | disclosed |
| CN-114544851-A | Analysis method for determining o-chlorobenzene glycine methyl ester tartrate and impurities | 苏州正济医药研究有限公司 | 2022-05-27 | — | — | CN | disclosed |
| CN-114544851-A | Analysis method for determining o-chlorobenzene glycine methyl ester tartrate and impurities | 苏州正济医药研究有限公司 | 2022-05-27 | — | — | CN | disclosed |
| EP-2931721-B1 | THIAZOLE DERIVATIVES AS INHIBITORS OF BRUTON'S TYROSINE KINASE | HOFFMANN LA ROCHE (CH) | 2016-10-26 | — | — | EP | disclosed |
| EP-2931721-B1 | THIAZOLE DERIVATIVES AS INHIBITORS OF BRUTON'S TYROSINE KINASE | HOFFMANN LA ROCHE (CH) | 2016-10-26 | — | — | EP | disclosed |
| US-9359345-B2 | Thiazole derivatives as inhibitors of Bruton's tyrosine kinase | HOFFMANN-LA ROCHE INC. (US) | 2016-06-07 | — | — | US | disclosed |
| US-9359345-B2 | Thiazole derivatives as inhibitors of Bruton's tyrosine kinase | HOFFMANN-LA ROCHE INC. (US) | 2016-06-07 | — | — | US | disclosed |
| US-9359345-B2 | Thiazole derivatives as inhibitors of Bruton's tyrosine kinase | HOFFMANN-LA ROCHE INC. (US) | 2016-06-07 | — | — | US | disclosed |
| WO-2014064131-A2 | INHIBITORS OF BRUTON'S TYROSINE KINASE | F. HOFFMANN-LA ROCHE AG (CH) | 2014-05-01 | — | — | WO | disclosed |
| EP-0900081-A4 | INHIBITORS OF FARNESYL-PROTEIN TRANSFERASE | MERCK & CO INC (US) | 2002-01-09 | — | — | EP | disclosed |
| EP-0891349-A4 | INHIBITORS OF FARNESYL-PROTEIN TRANSFERASE | MERCK & CO INC (US) | 2001-01-24 | — | — | EP | disclosed |
| US-5919785-A | Inhibitors of farnesyl-protein transferase | MERCK & CO., INC. (US) | 1999-07-06 | — | — | US | disclosed |
| EP-0900081-A1 | INHIBITORS OF FARNESYL-PROTEIN TRANSFERASE | Merck & Co., Inc. (US) | 1999-03-10 | — | — | EP | disclosed |
| EP-0891349-A1 | INHIBITORS OF FARNESYL-PROTEIN TRANSFERASE | Merck & Co., Inc. (US) | 1999-01-20 | — | — | EP | disclosed |
| WO-1997036591-A1 | INHIBITORS OF FARNESYL-PROTEIN TRANSFERASE | MERCK & CO., INC. (US) | 1997-10-09 | — | — | WO | disclosed |
| WO-1997036888-A1 | INHIBITORS OF FARNESYL-PROTEIN TRANSFERASE | MERCK & CO., INC. (US) | 1997-10-09 | — | — | WO | disclosed |
| US-4985427-A | LIPOXYGENASE INHIBITORS | GLAXO GROUP LIMITED (GB) | 1991-01-15 | — | — | US | disclosed |
| EP-0340030-A2 | Triazine derivatives | GLAXO GROUP LIMITED (GB) | 1989-11-02 | — | — | EP | disclosed |