SCHEMBL111160

SCHEMBL111160

C=C(C)C(=O)NCCNCC

nearest known ligand 0.34

Predicted protein targets (top 16)

geneUniProtsupporting neighboursconfidence
TGFBR1 P36897 1/20 0.34
CYP2C19 P33261 2/20 0.33
MEN1 O00255 1/20 0.33
GLA P06280 1/20 0.33
KMT2A Q03164 1/20 0.33
PAOX Q6QHF9 1/20 0.32
TSHR P16473 2/20 0.32
USP2 O75604 1/20 0.32
CYP1A2 P05177 1/20 0.32
THRB P10828 1/20 0.31
KDM4E B2RXH2 2/20 0.31
POLB P06746 1/20 0.31
ALDH1A1 P00352 1/20 0.31
MCL1 Q07820 1/20 0.30
MAPK1 P28482 1/20 0.30
HIF1A Q16665 1/20 0.30

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL16267884 0.89 TGFBR1 (0.38) TGFBR1MEN1KMT2APAOXTSHR
SCHEMBL110493 0.88 PAOX (0.47) CYP2C19MEN1GLAKMT2APAOX
SCHEMBL112008 0.88 CYP2C19 (0.46) CYP2C19MEN1GLAKMT2APAOX
SCHEMBL316224 0.86 TGFBR1 (0.41) TGFBR1CYP2C19PAOXTSHRUSP2
SCHEMBL107894 0.86 PAOX (0.46) CYP2C19MEN1GLAKMT2APAOX
Hydrochloric Acid SCHEMBL31441106 0.86 CYP2C19 (0.44) CYP2C19MEN1GLAKMT2APAOX
Diethylamine SCHEMBL721666 0.85 PAOX (0.39) TGFBR1KMT2APAOXTSHRTHRB
SCHEMBL3278602 0.85 PAOX (0.48) TGFBR1PAOXTSHRUSP2THRB
SCHEMBL7996060 0.82 ZDHHC20 (0.41) TSHRALDH1A1MAPK1
Diethylamine SCHEMBL721502 0.82 TGFBR1 (0.41) TGFBR1KMT2APAOXTHRBKDM4E

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 234 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-4121802-B1 HIGH REFRACTIVE INDEX SILOXANE INSERT MATERIALS FOR EMBEDDED CONTACT LENSES ALCON INC (CH) 2024-07-17 EP claimed
EP-4076916-B1 WETTABLE SILICONE HYDROGEL CONTACT LENSES ALCON INC (CH) 2024-06-12 EP claimed
EP-4121801-B1 INSERT MATERIALS WITH HIGH OXYGEN PERMEABILITY AND HIGH REFRACTIVE INDEX ALCON INC (CH) 2024-04-17 EP claimed
EP-4146461-B1 METHOD FOR PRODUCING SILICONE HYDROGEL CONTACT LENSES ALCON INC (CH) 2024-03-13 EP claimed
EP-4118134-B1 PHOTOCHROMIC POLYDIORGANOSILOXANE VINYLIC CROSSLINKERS ALCON INC (CH) 2024-02-28 EP claimed
EP-3802080-B1 METHOD FOR MAKING SILICONE HYDROGEL CONTACT LENSES ALCON INC (CH) 2023-07-19 EP claimed
EP-3976362-B1 METHOD FOR MAKING OPAQUE COLORED SILICONE HYDROGEL CONTACT LENSES ALCON INC (CH) 2023-06-07 EP claimed
EP-3774310-B1 METHOD FOR MAKING SILICONE HYDROGEL CONTACT LENSES ALCON INC (CH) 2022-07-06 EP claimed
EP-3746820-B1 CONTACT LENSES WITH A LUBRICIOUS COATING THEREON ALCON INC (CH) 2022-02-16 EP claimed
US-7700540-B2 Hard surface cleaning composition THE CLOROX COMPANY (US) 2010-04-20 US claimed
US-20070099816-A1 Hard Surface Cleaning Composition THE CLOROX COMPANY 2007-05-03 US claimed
US-20060181587-A1 Ink set and media for ink-jet printing HEWLETT-PACKARD DEVELOPMENT COMPANY, L.P. 2006-08-17 US claimed
EP-0657751-B1 Soft ocular lens material MENICON CO LTD (JP) 2003-04-23 EP claimed
US-4829126-A COPOLYMER OF ACRYLATE HAVING HYDROPHILIC GROUP AND N-VINYLLACTAM OR ACRYLAMIDE TOYO CONTACT LENS CO., LTD. (JP) 1989-05-09 US claimed
EP-3870656-B1 ACRYLIC POLYMERS FOR INKJET INK APPLICATIONS CABOT CORP (US) 2026-03-18 EP disclosed
US-12018162-B2 Acrylic polymers for inkjet ink applications CABOT CORPORATION (US) 2024-06-25 US disclosed
WO-2024116990-A1 FRICTION MODIFIER AND LUBRICANT COMPOSITION 三洋化成工業株式会社 2024-06-06 WO disclosed
WO-1983002115-A1 CATIONIC ACRYLAMIDE AND RUBBER MODIFIED ASPHALTS OWENS CORNING FIBERGLASS CORP (US) 1983-06-23 WO disclosed
EP-0082056-A1 Cationic acrylamide and rubber modified asphalts OWENS-CORNING FIBERGLAS CORPORATION (US) 1983-06-22 EP disclosed
US-4383081-A Cationic acrylamide chemically modified asphalts OWENS-CORNING FIBERGLAS CORPORATION (US) 1983-05-10 US disclosed