Predicted protein targets (top 8)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | REN | P00797 | 1/20 | 0.47 |
| ▸ | CTSS | P25774 | 1/20 | 0.44 |
| ▸ | CTSK | P43235 | 1/20 | 0.44 |
| ▸ | OPRD1 | P41143 | 15/20 | 0.43 |
| ▸ | OPRM1 | P35372 | 6/20 | 0.43 |
| ▸ | OPRK1 | P41145 | 2/20 | 0.43 |
| ▸ | CCKBR | P32239 | 3/20 | 0.39 |
| ▸ | CCKAR | P32238 | 2/20 | 0.39 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL10630954 | 0.85 | REN (0.49) | RENOPRD1OPRM1OPRK1 | |
| SCHEMBL10707861 | 0.84 | CTSS (0.44) | RENCTSSCTSKOPRD1CCKBR | |
| SCHEMBL20440150 | 0.80 | CTSS (0.45) | RENCTSSCTSKOPRD1OPRM1 | |
| SCHEMBL4018243 | 0.80 | CTSS (0.66) | CTSSCTSKOPRD1OPRM1OPRK1 | |
| SCHEMBL11683746 | 0.80 | CTSS (0.66) | CTSSCTSKOPRD1OPRM1OPRK1 | |
| SCHEMBL4018237 | 0.80 | CTSS (0.66) | CTSSCTSKOPRD1OPRM1OPRK1 | |
| SCHEMBL4778626 | 0.79 | CTSS (0.44) | RENCTSSCTSKOPRD1OPRM1 | |
| SCHEMBL6661008 | 0.79 | CTSS (0.44) | RENCTSSCTSKOPRD1OPRM1 | |
| SCHEMBL8766144 | 0.79 | CTSS (0.44) | RENCTSSCTSKOPRD1OPRM1 | |
| SCHEMBL11443642 | 0.78 | REN (0.47) | RENCTSK |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0122018-A2 | Improvements in and relating to pharmacologically active tripeptide derivatives | ELI LILLY AND COMPANY (US) | 1984-10-17 | — | — | EP | disclosed |