SCHEMBL11116156

SCHEMBL11116156

C=CCO[Si](OC)(OC)C(=O)C(=C)C

nearest known ligand 0.31

Predicted protein targets (top 1)

geneUniProtsupporting neighboursconfidence
ALDH1A1 P00352 1/20 0.31

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL1491040 0.77 ALDH1A1 (0.43) ALDH1A1
Propane SCHEMBL27604486 0.76 ALDH1A1 (0.39) ALDH1A1
Propane SCHEMBL27604335 0.74 TSHR (0.33) ALDH1A1
SCHEMBL14721697 0.73 ALDH1A1 (0.33) ALDH1A1
SCHEMBL29047230 0.68 CYP3A4 (0.31)
SCHEMBL5700760 0.67 CYP3A4 (0.32) ALDH1A1
SCHEMBL2257878 0.67 THRB (0.38) ALDH1A1
SCHEMBL11116152 0.67
SCHEMBL30054072 0.65 TSHR (0.31)
SCHEMBL27883317 0.65 ALDH1A1 (0.40) ALDH1A1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 6 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-0030513-B1 COMPOSITIONS BASED ON A POLYAMIDE, GLASS FIBRES AND AN UNSATURATED ACRYLIC COMPOSITION RHONE-POULENC SPECIALITES CHIMIQUES (FR) 1984-09-05 EP disclosed
US-4363894-A Glass reinforced polyamide compositions having improved impact strengths RHONE-POULENC INDUSTRIES (FR) 1982-12-14 US disclosed
US-4362832-A Thermoplastic polymer/glass fiber/bis-maleimide molding compositions RHONE-POULENC INDUSTRIES (FR) 1982-12-07 US disclosed
EP-0030513-A1 Compositions based on a polyamide, glass fibres and an unsaturated acrylic composition RHONE-POULENC SPECIALITES CHIMIQUES (FR) 1981-06-17 EP disclosed
US-4260539-A Polypropylene/glass fiber/imido prepolymer based compositions RHONE-POULENC INDUSTRIES (FR) 1981-04-07 US disclosed
US-4224216-A Polypropylene/glass fiber/imide/thermoplastic elastomer based compositions RHONE-POULENC INDUSTRIES (FR) 1980-09-23 US disclosed