Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MEN1 | O00255 | 3/20 | 0.40 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.40 |
| ▸ | KDM4E | B2RXH2 | 3/20 | 0.39 |
| ▸ | GLA | P06280 | 1/20 | 0.39 |
| ▸ | GAA | P10253 | 1/20 | 0.39 |
| ▸ | GABRA1 | P14867 | 1/20 | 0.38 |
| ▸ | GABRB2 | P47870 | 1/20 | 0.38 |
| ▸ | CYP1A2 | P05177 | 2/20 | 0.38 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.38 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.38 |
| ▸ | MAPT | P10636 | 2/20 | 0.33 |
| ▸ | TSHR | P16473 | 1/20 | 0.33 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.33 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.32 |
| ▸ | ALOX12 | P18054 | 1/20 | 0.32 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.32 |
| ▸ | ERN1 | O75460 | 1/20 | 0.31 |
| ▸ | TRPV4 | Q9HBA0 | 1/20 | 0.31 |
| ▸ | MAOB | P27338 | 1/20 | 0.31 |
| ▸ | ESR1 | P03372 | 1/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL29249591 | 0.86 | MEN1 (0.42) | MEN1KMT2AKDM4ECYP1A2MAPT | |
| SCHEMBL17377707 | 0.78 | GABRA1 (0.43) | MEN1KMT2AGABRA1GABRB2CYP1A2 | |
| SCHEMBL5200570 | 0.76 | MEN1 (0.40) | MEN1KMT2AKDM4EGABRA1GABRB2 | |
| SCHEMBL28318019 | 0.75 | MAOB (0.39) | MAOB | |
| SCHEMBL5165075 | 0.75 | MEN1 (0.66) | MEN1KMT2ACYP1A2CYP3A4CYP2C9 | |
| SCHEMBL25328782 | 0.75 | GABRA1 (0.42) | MEN1KMT2AKDM4EGLAGAA | |
| SCHEMBL31092542 | 0.75 | GABRA1 (0.42) | MEN1KMT2AKDM4EGLAGAA | |
| SCHEMBL5786389 | 0.74 | HTT (0.42) | MEN1KMT2AKDM4ECYP1A2CYP3A4 | |
| SCHEMBL31092541 | 0.73 | GABRA1 (0.41) | MEN1KMT2AKDM4EGLAGAA | |
| SCHEMBL25327893 | 0.73 | GABRA1 (0.41) | MEN1KMT2AKDM4EGLAGAA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0104018-A2 | Benzopyran, benzothiapyran and quinoline compounds and pharmaceutical compositions containing them | FISONS plc (GB) | 1984-03-28 | — | — | EP | disclosed |