Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TYR | P14679 | 1/20 | 0.50 |
| ▸ | RAB9A | P51151 | 3/20 | 0.48 |
| ▸ | NPC1 | O15118 | 2/20 | 0.48 |
| ▸ | MEN1 | O00255 | 1/20 | 0.48 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.48 |
| ▸ | KDM1A | O60341 | 2/20 | 0.45 |
| ▸ | ATM | Q13315 | 2/20 | 0.44 |
| ▸ | SMN1; SMN2 | Q16637 | 3/20 | 0.42 |
| ▸ | CASP3 | P42574 | 1/20 | 0.42 |
| ▸ | SENP8 | Q96LD8 | 1/20 | 0.42 |
| ▸ | LIMK1 | P53667 | 1/20 | 0.42 |
| ▸ | LIMK2 | P53671 | 1/20 | 0.42 |
| ▸ | LMNA | P02545 | 2/20 | 0.42 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.42 |
| ▸ | MAP3K14 | Q99558 | 1/20 | 0.42 |
| ▸ | ROCK2 | O75116 | 1/20 | 0.41 |
| ▸ | PIM1 | P11309 | 1/20 | 0.41 |
| ▸ | GSK3B | P49841 | 1/20 | 0.41 |
| ▸ | AURKB | Q96GD4 | 1/20 | 0.41 |
| ▸ | GAA | P10253 | 1/20 | 0.40 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL11116104 | 0.89 | TYR (0.50) | TYRRAB9ANPC1MEN1KMT2A | |
| SCHEMBL11116275 | 0.85 | NPC1 (0.47) | TYRRAB9ANPC1MEN1KMT2A | |
| SCHEMBL9858147 | 0.84 | HDAC1 (0.50) | MEN1KMT2AKDM1AATML3MBTL1 | |
| SCHEMBL11116177 | 0.82 | KDM1A (0.49) | TYRRAB9ANPC1MEN1KMT2A | |
| SCHEMBL9858012 | 0.80 | CYP2C19 (0.56) | RAB9AMEN1KMT2AATMSMN1; SMN2 | |
| SCHEMBL10662617 | 0.79 | TYR (0.53) | TYRRAB9ANPC1MEN1KMT2A | |
| Hydrochloric Acid SCHEMBL10667322 | 0.78 | TYR (0.52) | TYRRAB9ANPC1MEN1KMT2A | |
| SCHEMBL11119957 | 0.76 | TYR (0.51) | TYRSMN1; SMN2LMNAL3MBTL1ROCK2 | |
| SCHEMBL10667317 | 0.76 | TYR (0.53) | TYRRAB9ANPC1MEN1KMT2A | |
| SCHEMBL9858110 | 0.75 | CA5A (0.57) | TYRRAB9ANPC1MEN1KMT2A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0114347-A2 | Aralkyl-triazole compounds | CIBA-GEIGY AG (CH) | 1984-08-01 | — | — | EP | claimed |
| EP-0114347-A2 | Aralkyl-triazole compounds | CIBA-GEIGY AG (CH) | 1984-08-01 | — | — | EP | disclosed |