Predicted protein targets (top 19)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HDAC1 | Q13547 | 1/20 | 0.50 |
| ▸ | KDM1A | O60341 | 6/20 | 0.45 |
| ▸ | ATM | Q13315 | 1/20 | 0.44 |
| ▸ | L3MBTL1 | Q9Y468 | 2/20 | 0.44 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.43 |
| ▸ | MEN1 | O00255 | 1/20 | 0.43 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.43 |
| ▸ | KDM1B | Q8NB78 | 1/20 | 0.43 |
| ▸ | MAPT | P10636 | 2/20 | 0.43 |
| ▸ | PKM | P14618 | 1/20 | 0.43 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.42 |
| ▸ | CA5A | P35218 | 1/20 | 0.42 |
| ▸ | ROCK2 | O75116 | 1/20 | 0.41 |
| ▸ | PAK4 | O96013 | 1/20 | 0.41 |
| ▸ | PIM1 | P11309 | 1/20 | 0.41 |
| ▸ | GSK3B | P49841 | 1/20 | 0.41 |
| ▸ | AURKB | Q96GD4 | 1/20 | 0.41 |
| ▸ | CYP19A1 | P11511 | 1/20 | 0.40 |
| ▸ | KCNMA1 | Q12791 | 1/20 | 0.39 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9858306 | 0.88 | HDAC1 (0.49) | HDAC1KDM1AATML3MBTL1ALDH1A1 | |
| SCHEMBL9858277 | 0.85 | CA5A (0.59) | HDAC1KDM1AALDH1A1KDM4ECA5A | |
| SCHEMBL11116350 | 0.84 | TYR (0.50) | KDM1AATML3MBTL1ALDH1A1MEN1 | |
| SCHEMBL9858012 | 0.80 | CYP2C19 (0.56) | ATMALDH1A1MEN1KMT2AMAPT | |
| SCHEMBL9858144 | 0.79 | CA5A (0.55) | HDAC1KDM1AATML3MBTL1ALDH1A1 | |
| Hydrochloric Acid SCHEMBL10667411 | 0.78 | CA5A (0.53) | HDAC1KDM1AATML3MBTL1ALDH1A1 | |
| SCHEMBL30645406 | 0.75 | CA5A (0.72) | HDAC1KDM1AATML3MBTL1ALDH1A1 | |
| SCHEMBL10667399 | 0.75 | CA5A (0.53) | HDAC1KDM1AATML3MBTL1ALDH1A1 | |
| SCHEMBL9857405 | 0.75 | CA5A (0.72) | HDAC1KDM1AATML3MBTL1ALDH1A1 | |
| SCHEMBL7137288 | 0.73 | CA5A (0.65) | HDAC1KDM1AALDH1A1KDM4ECA5A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0199262-B1 | FLUORINATED BENZYL TRIAZOLE COMPOUNDS | CIBA-GEIGY AG (CH) | 1991-02-27 | — | — | EP | disclosed |
| EP-0199262-A2 | Fluorinated benzyl triazole compounds | CIBA-GEIGY AG (CH) | 1986-10-29 | — | — | EP | disclosed |