Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CYP2C19 | P33261 | 1/20 | 0.56 |
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.54 |
| ▸ | LMNA | P02545 | 2/20 | 0.54 |
| ▸ | CA5A | P35218 | 1/20 | 0.50 |
| ▸ | EGFR | P00533 | 1/20 | 0.44 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.42 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.42 |
| ▸ | KDM4E | B2RXH2 | 4/20 | 0.42 |
| ▸ | POLB | P06746 | 2/20 | 0.41 |
| ▸ | PKM | P14618 | 1/20 | 0.41 |
| ▸ | TSHR | P16473 | 1/20 | 0.41 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.41 |
| ▸ | KMT2A | Q03164 | 4/20 | 0.40 |
| ▸ | MEN1 | O00255 | 3/20 | 0.40 |
| ▸ | MAPT | P10636 | 2/20 | 0.40 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.40 |
| ▸ | RAB9A | P51151 | 1/20 | 0.40 |
| ▸ | ATM | Q13315 | 1/20 | 0.40 |
| ▸ | SLC22A12 | Q96S37 | 2/20 | 0.40 |
| ▸ | ALKBH1 | Q13686 | 1/20 | 0.40 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9858277 | 0.91 | CA5A (0.59) | CYP2C19ALDH1A1LMNACA5AEGFR | |
| SCHEMBL9858008 | 0.81 | CYP2C19 (0.65) | CYP2C19ALDH1A1LMNACA5AEGFR | |
| SCHEMBL27949718 | 0.80 | CA5A (0.58) | CYP2C19ALDH1A1LMNACA5AEGFR | |
| SCHEMBL7137288 | 0.80 | CA5A (0.65) | CYP2C19ALDH1A1LMNACA5AEGFR | |
| SCHEMBL9858147 | 0.80 | HDAC1 (0.50) | ALDH1A1CA5AKDM4EPKMKMT2A | |
| SCHEMBL11116350 | 0.80 | TYR (0.50) | CYP2C19ALDH1A1LMNASMN1; SMN2KMT2A | |
| SCHEMBL9857399 | 0.78 | CA5A (0.82) | CYP2C19ALDH1A1LMNACA5AEGFR | |
| SCHEMBL11119957 | 0.75 | TYR (0.51) | ALDH1A1LMNATDP1KDM4EPOLB | |
| SCHEMBL9858306 | 0.71 | HDAC1 (0.49) | ALDH1A1CA5AKDM4EPKMKMT2A | |
| SCHEMBL460913 | 0.71 | CA5A (0.76) | CYP2C19ALDH1A1LMNACA5ASMN1; SMN2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0199262-B1 | FLUORINATED BENZYL TRIAZOLE COMPOUNDS | CIBA-GEIGY AG (CH) | 1991-02-27 | — | — | EP | disclosed |
| EP-0199262-A2 | Fluorinated benzyl triazole compounds | CIBA-GEIGY AG (CH) | 1986-10-29 | — | — | EP | disclosed |