SCHEMBL11116465

SCHEMBL11116465

Cc1ccc(S(=O)(=O)N(F)C2CCCCC2)cc1

nearest known ligand 0.50

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
CNR1 P21554 2/20 0.50
CNR2 P34972 2/20 0.50
POLB P06746 1/20 0.50
ALDH1A1 P00352 8/20 0.49
MEN1 O00255 3/20 0.49
KMT2A Q03164 3/20 0.49
CYP3A4 P08684 2/20 0.49
KDM4E B2RXH2 1/20 0.49
TSHR P16473 1/20 0.49
HTR2A P28223 1/20 0.48
HTR2C P28335 1/20 0.48
MAPT P10636 3/20 0.46
LMNA P02545 1/20 0.46
GAA P10253 1/20 0.46
NPSR1 Q6W5P4 4/20 0.45
TP53 P04637 2/20 0.45
ALOX15 P16050 1/20 0.45
MAPK1 P28482 1/20 0.45
L3MBTL1 Q9Y468 1/20 0.45
ACHE P22303 1/20 0.45

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL3699604 0.83 POLB (0.54) CNR1CNR2POLBALDH1A1MEN1
SCHEMBL9303072 0.81 ALDH1A1 (0.73) CNR1CNR2POLBALDH1A1MEN1
SCHEMBL3280160 0.80 POLB (0.54) CNR1CNR2POLBALDH1A1MEN1
SCHEMBL11709606 0.79 CNR1 (0.49) CNR1CNR2POLBALDH1A1MEN1
SCHEMBL11708553 0.79 CNR1 (0.49) CNR1CNR2POLBALDH1A1MEN1
SCHEMBL29165184 0.78 CNR1 (0.48) CNR1CNR2POLBALDH1A1MEN1
SCHEMBL11710002 0.77 CNR1 (0.48) CNR1CNR2POLBALDH1A1MEN1
SCHEMBL11705624 0.77 CNR1 (0.48) CNR1CNR2POLBALDH1A1MEN1
SCHEMBL11706992 0.74 CNR1 (0.46) CNR1CNR2POLBALDH1A1MEN1
SCHEMBL3909934 0.74 ALDH1A1 (0.67) CNR1CNR2POLBALDH1A1MEN1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-4479901-A Fluorination of carbanions with N-fluoro-N-alkylsulfonamides E. I. DU PONT DE NEMOURS AND COMPANY (US) 1984-10-30 US disclosed