Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | NPC1 | O15118 | 3/20 | 0.57 |
| ▸ | RAB9A | P51151 | 3/20 | 0.57 |
| ▸ | LMNA | P02545 | 1/20 | 0.57 |
| ▸ | PTGS1 | P23219 | 7/20 | 0.41 |
| ▸ | PTGS2 | P35354 | 6/20 | 0.41 |
| ▸ | NQO2 | P16083 | 2/20 | 0.41 |
| ▸ | ESR1 | P03372 | 1/20 | 0.40 |
| ▸ | ESR2 | Q92731 | 1/20 | 0.40 |
| ▸ | TUBB1 | Q9H4B7 | 1/20 | 0.39 |
| ▸ | RARA | P10276 | 1/20 | 0.37 |
| ▸ | RARB | P10826 | 1/20 | 0.37 |
| ▸ | RARG | P13631 | 1/20 | 0.37 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.37 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.37 |
| ▸ | POLB | P06746 | 1/20 | 0.36 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.36 |
| ▸ | HPGD | P15428 | 1/20 | 0.36 |
| ▸ | EGFR | P00533 | 1/20 | 0.35 |
| ▸ | ERBB2 | P04626 | 1/20 | 0.35 |
| ▸ | MEN1 | O00255 | 1/20 | 0.35 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL14126172 | 0.80 | NPC1 (0.66) | NPC1RAB9ALMNAALDH1A1SMN1; SMN2 | |
| Acetic Acid SCHEMBL6571740 | 0.79 | NPC1 (0.56) | NPC1RAB9ALMNAESR1ESR2 | |
| SCHEMBL22060978 | 0.78 | RAB9A (0.50) | NPC1RAB9ALMNAPTGS1PTGS2 | |
| SCHEMBL28696120 | 0.78 | NPC1 (0.62) | NPC1RAB9ALMNAALDH1A1SMN1; SMN2 | |
| SCHEMBL10728649 | 0.77 | RAB9A (0.61) | NPC1RAB9ALMNAPTGS2ALDH1A1 | |
| SCHEMBL251422 | 0.77 | NPC1 (0.61) | NPC1RAB9ALMNAALDH1A1SMN1; SMN2 | |
| SCHEMBL25184975 | 0.77 | CYP3A4 (0.52) | NPC1RAB9ALMNAALDH1A1HPGD | |
| SCHEMBL30382840 | 0.77 | CYP3A4 (0.52) | NPC1RAB9ALMNAALDH1A1HPGD | |
| SCHEMBL178513 | 0.75 | NPC1 (0.55) | NPC1RAB9ALMNAPTGS2RARA | |
| SCHEMBL8446654 | 0.75 | NPC1 (0.51) | NPC1RAB9ALMNAALDH1A1SMN1; SMN2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-4426472-A | TETRAALKYLPIPERIDINES | CIBA-GEIGY CORPORATION (US) | 1984-01-17 | — | — | US | disclosed |