Predicted protein targets (top 19)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | NPC1 | O15118 | 4/20 | 0.55 |
| ▸ | RAB9A | P51151 | 4/20 | 0.55 |
| ▸ | LMNA | P02545 | 1/20 | 0.55 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.36 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.36 |
| ▸ | POLB | P06746 | 4/20 | 0.35 |
| ▸ | MEN1 | O00255 | 2/20 | 0.34 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.34 |
| ▸ | MAPT | P10636 | 2/20 | 0.32 |
| ▸ | USP2 | O75604 | 1/20 | 0.32 |
| ▸ | KDM4E | B2RXH2 | 3/20 | 0.32 |
| ▸ | PPARG | P37231 | 1/20 | 0.32 |
| ▸ | PPARA | Q07869 | 1/20 | 0.32 |
| ▸ | HPGD | P15428 | 1/20 | 0.31 |
| ▸ | RARA | P10276 | 1/20 | 0.31 |
| ▸ | RARB | P10826 | 1/20 | 0.31 |
| ▸ | RARG | P13631 | 1/20 | 0.31 |
| ▸ | PTGS2 | P35354 | 1/20 | 0.30 |
| ▸ | MYC | P01106 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9638138 | 0.79 | NPC1 (0.62) | NPC1RAB9ALMNAALDH1A1SMN1; SMN2 | |
| SCHEMBL10546687 | 0.79 | NPC1 (0.62) | NPC1RAB9ALMNAALDH1A1SMN1; SMN2 | |
| SCHEMBL11116579 | 0.75 | NPC1 (0.57) | NPC1RAB9ALMNAALDH1A1SMN1; SMN2 | |
| SCHEMBL5718619 | 0.74 | NPC1 (0.56) | NPC1RAB9ALMNAALDH1A1SMN1; SMN2 | |
| SCHEMBL29512561 | 0.74 | NPC1 (0.56) | NPC1RAB9ALMNAALDH1A1SMN1; SMN2 | |
| SCHEMBL29354646 | 0.74 | NPC1 (0.64) | NPC1RAB9ALMNAALDH1A1SMN1; SMN2 | |
| SCHEMBL78159 | 0.74 | NPC1 (0.64) | NPC1RAB9ALMNAALDH1A1SMN1; SMN2 | |
| SCHEMBL2797053 | 0.74 | NPC1 (0.59) | NPC1RAB9ALMNAALDH1A1SMN1; SMN2 | |
| SCHEMBL31309385 | 0.74 | NPC1 (0.59) | NPC1RAB9ALMNAALDH1A1SMN1; SMN2 | |
| SCHEMBL29007118 | 0.73 | NPC1 (0.55) | NPC1RAB9ALMNAALDH1A1SMN1; SMN2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20120059095-A1 | HIGH MOLECULAR WEIGHT NONPOLAR BENZOTRIAZOLES | BASF SE (DE) | 2012-03-08 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20120059095-A1 | HIGH MOLECULAR WEIGHT NONPOLAR BENZOTRIAZOLES | SULT1A1, TPST2, SULT2A1 | NPC1 4231/4885RAB9A 4877/4885LMNA 3686/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.