Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | NR4A2 | P43354 | 1/20 | 0.55 |
| ▸ | KMT2A | Q03164 | 6/20 | 0.48 |
| ▸ | PKM | P14618 | 1/20 | 0.48 |
| ▸ | MAPT | P10636 | 2/20 | 0.48 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.48 |
| ▸ | ESR1 | P03372 | 2/20 | 0.48 |
| ▸ | ESR2 | Q92731 | 2/20 | 0.48 |
| ▸ | HSD17B10 | Q99714 | 2/20 | 0.48 |
| ▸ | MEN1 | O00255 | 1/20 | 0.48 |
| ▸ | JAK2 | O60674 | 1/20 | 0.48 |
| ▸ | USP2 | O75604 | 1/20 | 0.48 |
| ▸ | GAA | P10253 | 1/20 | 0.48 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.48 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.48 |
| ▸ | RORC | P51449 | 4/20 | 0.45 |
| ▸ | CA12 | O43570 | 1/20 | 0.44 |
| ▸ | CA1 | P00915 | 1/20 | 0.44 |
| ▸ | CA2 | P00918 | 1/20 | 0.44 |
| ▸ | CA9 | Q16790 | 1/20 | 0.44 |
| ▸ | TNF | P01375 | 1/20 | 0.43 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL30234406 | 0.90 | ALDH1A1 (0.50) | NR4A2KMT2APKMMAPTSMN1; SMN2 | |
| SCHEMBL11114973 | 0.88 | KMT2A (0.55) | NR4A2KMT2APKMMAPTUSP2 | |
| SCHEMBL7431522 | 0.83 | NR4A2 (0.56) | NR4A2SMN1; SMN2ESR1HSD17B10CA12 | |
| SCHEMBL28389039 | 0.83 | LMNA (0.50) | NR4A2KMT2APKMMAPTSMN1; SMN2 | |
| SCHEMBL4664127 | 0.79 | NR4A2 (0.49) | NR4A2RORCCA12CA1CA2 | |
| SCHEMBL12641988 | 0.78 | HCRTR1 (0.49) | KMT2APKMMAPTSMN1; SMN2ESR1 | |
| SCHEMBL13335079 | 0.77 | NR4A2 (0.50) | NR4A2RORCKDM4EPOLBCTDSP1 | |
| SCHEMBL27840811 | 0.75 | KMT2A (0.43) | KMT2APKMMAPTSMN1; SMN2ESR1 | |
| SCHEMBL28878338 | 0.74 | NR4A2 (0.55) | NR4A2KMT2AMAPTHSD17B10MEN1 | |
| SCHEMBL9796603 | 0.74 | POLB (0.52) | NR4A2KMT2APKMMAPTSMN1; SMN2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0116360-A1 | 1-Phenyl-2-aminocarbonyl indoles, their preparation and medicines containing them | Kali-Chemie Pharma GmbH (DE) | 1984-08-22 | — | — | EP | disclosed |