Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KMT2A | Q03164 | 4/20 | 0.55 |
| ▸ | MAPT | P10636 | 2/20 | 0.55 |
| ▸ | PKM | P14618 | 1/20 | 0.55 |
| ▸ | KDM4E | B2RXH2 | 3/20 | 0.47 |
| ▸ | GAA | P10253 | 1/20 | 0.47 |
| ▸ | NR4A2 | P43354 | 1/20 | 0.47 |
| ▸ | RORC | P51449 | 4/20 | 0.46 |
| ▸ | LMNA | P02545 | 1/20 | 0.45 |
| ▸ | TP53 | P04637 | 1/20 | 0.45 |
| ▸ | ELANE | P08246 | 2/20 | 0.43 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.43 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.43 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.43 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.43 |
| ▸ | USP2 | O75604 | 1/20 | 0.42 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.42 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.42 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.42 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.41 |
| ▸ | POLB | P06746 | 1/20 | 0.41 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL11116979 | 0.88 | NR4A2 (0.55) | KMT2AMAPTPKMKDM4EGAA | |
| SCHEMBL30234406 | 0.80 | ALDH1A1 (0.50) | KMT2AMAPTPKMKDM4EGAA | |
| SCHEMBL7431522 | 0.76 | NR4A2 (0.56) | KDM4ENR4A2LMNAALDH1A1 | |
| SCHEMBL27840811 | 0.73 | KMT2A (0.43) | KMT2AMAPTPKMKDM4EGAA | |
| SCHEMBL28389039 | 0.73 | LMNA (0.50) | KMT2AMAPTPKMGAANR4A2 | |
| SCHEMBL21999712 | 0.73 | KMT2A (0.70) | KMT2AMAPTPKMKDM4EGAA | |
| SCHEMBL4664127 | 0.72 | NR4A2 (0.49) | KDM4ENR4A2RORCALDH1A1 | |
| SCHEMBL6057189 | 0.72 | KDM4E (0.68) | KMT2AMAPTPKMKDM4EGAA | |
| SCHEMBL30721452 | 0.72 | KDM4E (0.68) | KMT2AMAPTPKMKDM4EGAA | |
| SCHEMBL29176614 | 0.72 | MAOB (0.60) | KMT2AMAPTKDM4ENR4A2RORC |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0116360-A1 | 1-Phenyl-2-aminocarbonyl indoles, their preparation and medicines containing them | Kali-Chemie Pharma GmbH (DE) | 1984-08-22 | — | — | EP | disclosed |